Literature DB >> 17056754

Response of Staphylococcus aureus to salicylate challenge.

James T Riordan1, Arunachalam Muthaiyan, Wayne Van Voorhies, Christopher T Price, James E Graham, Brian J Wilkinson, John E Gustafson.   

Abstract

Growth of Staphylococcus aureus with the nonsteroidal anti-inflammatory salicylate reduces susceptibility of the organism to multiple antimicrobials. Transcriptome analysis revealed that growth of S. aureus with salicylate leads to the induction of genes involved with gluconate and formate metabolism and represses genes required for gluconeogenesis and glycolysis. In addition, salicylate induction upregulates two antibiotic target genes and downregulates a multidrug efflux pump gene repressor (mgrA) and sarR, which represses a gene (sarA) important for intrinsic antimicrobial resistance. We hypothesize that these salicylate-induced alterations jointly represent a unique mechanism that allows S. aureus to resist antimicrobial stress and toxicity.

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Year:  2006        PMID： 17056754      PMCID： PMC1797221          DOI： 10.1128/JB.01149-06

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  52 in total

1.  Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics.

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Journal:  Biochem Biophys Res Commun       Date:  1968-02-15       Impact factor: 3.575

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Journal:  J Bacteriol       Date:  2005-04       Impact factor: 3.490

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Authors:  Y Fujita; T Fujita
Journal:  J Bacteriol       Date:  1983-05       Impact factor: 3.490

5.  Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate.

Authors:  Amy C Nulton-Persson; Luke I Szweda; Hesham A Sadek
Journal:  J Cardiovasc Pharmacol       Date:  2004-11       Impact factor: 3.105

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Authors:  A C Beynen; K F Buechler; A J van der Molen; M J Geelen
Journal:  Toxicology       Date:  1982       Impact factor: 4.221

7.  Effects of sarA inactivation on the intrinsic multidrug resistance mechanism of Staphylococcus aureus.

Authors:  Jessica O O'Leary; Mark J Langevin; Christopher T D Price; Jon S Blevins; Mark S Smeltzer; John E Gustafson
Journal:  FEMS Microbiol Lett       Date:  2004-08-15       Impact factor: 2.742

8.  Effect of substrate exposure and other growth condition manipulations on norA expression.

Authors:  Glenn W Kaatz; Susan M Seo
Journal:  J Antimicrob Chemother       Date:  2004-07-01       Impact factor: 5.790

9.  Quinolone resistance due to reduced target enzyme expression.

Authors:  Dilek Ince; David C Hooper
Journal:  J Bacteriol       Date:  2003-12       Impact factor: 3.490

10.  Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus.

Authors:  Adhar C Manna; Susham S Ingavale; MaryBeth Maloney; Willem van Wamel; Ambrose L Cheung
Journal:  J Bacteriol       Date:  2004-08       Impact factor: 3.490
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  23 in total

Review 1.  Efflux-mediated drug resistance in bacteria: an update.

Authors:  Xian-Zhi Li; Hiroshi Nikaido
Journal:  Drugs       Date:  2009-08-20       Impact factor: 9.546

2.  Transcriptome analysis of alkali shock and alkali adaptation in Listeria monocytogenes 10403S.

Authors:  Efstathios S Giotis; Arunachalam Muthaiyan; Senthil Natesan; Brian J Wilkinson; Ian S Blair; David A McDowell
Journal:  Foodborne Pathog Dis       Date:  2010-10       Impact factor: 3.171

3.  Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.

Authors:  Fei Sun; Lu Zhou; Bing-Chuan Zhao; Xin Deng; Hoonsik Cho; Chengqi Yi; Xing Jian; Chun-Xiao Song; Chi-Hao Luan; Taeok Bae; Zigang Li; Chuan He
Journal:  Chem Biol       Date:  2011-08-26

4.  Tea tree oil-induced transcriptional alterations in Staphylococcus aureus.

Authors:  Jesus A Cuaron; Santosh Dulal; Yang Song; Atul K Singh; Cesar E Montelongo; Wanqin Yu; Vijayaraj Nagarajan; Radheshyam K Jayaswal; Brian J Wilkinson; John E Gustafson
Journal:  Phytother Res       Date:  2012-05-23       Impact factor: 5.878

5.  Salicylic acid diminishes Staphylococcus aureus capsular polysaccharide type 5 expression.

Authors:  Lucía P Alvarez; María S Barbagelata; Mariana Gordiola; Ambrose L Cheung; Daniel O Sordelli; Fernanda R Buzzola
Journal:  Infect Immun       Date:  2009-12-14       Impact factor: 3.441

6.  The fusidic acid stimulon of Staphylococcus aureus.

Authors:  Alejandro Delgado; Shahrear Zaman; Arunachalam Muthaiyan; Vijayaraj Nagarajan; Mohamed O Elasri; Brian J Wilkinson; John E Gustafson
Journal:  J Antimicrob Chemother       Date:  2008-09-10       Impact factor: 5.790

7.  sarA inactivation reduces vancomycin-intermediate and ciprofloxacin resistance expression by Staphylococcus aureus.

Authors:  Reena Lamichhane-Khadka; Stephanie A Cantore; James T Riordan; Alejandro Delgado; Alesha E A Norman; Sarah Dueñas; Shahrear Zaman; Sonia Horan; Brian J Wilkinson; John E Gustafson
Journal:  Int J Antimicrob Agents       Date:  2009-03-25       Impact factor: 5.283

8.  The isolation of Staphylococcus aureus tea tree oil-reduced susceptibility mutants.

Authors:  Jesus A Cuaron; Santosh Dulal; Peter H Cooke; Nathanial J Torres; John E Gustafson
Journal:  Phytother Res       Date:  2014-02-12       Impact factor: 5.878

9.  Genetic changes that correlate with the pine-oil disinfectant-reduced susceptibility mechanism of Staphylococcus aureus.

Authors:  R Lamichhane-Khadka; J T Riordan; A Delgado; A Muthaiyan; T D Reynolds; B J Wilkinson; J E Gustafson
Journal:  J Appl Microbiol       Date:  2008-12       Impact factor: 3.772

10.  Complex gene response of herbicide-resistant Enterobacter strain NRS-1 under different glyphosate stresses.

Authors:  Yun-Yan Fei; Javaid Akhter Bhat; Ying-Ying Zhang; G M Al Amin; Jun-Yi Gai; Tuan-Jie Zhao
Journal:  3 Biotech       Date:  2018-09-27       Impact factor: 2.406
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