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Literature DB >> 17056629

Administration of testosterone results in reversible deterioration in Kennedy's disease.

P Kinirons¹, G A Rouleau.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 2006 PMID： 17056629 DOI： 10.1136/jnnp.2006.101899

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

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11 in total

1. Androgen receptors in muscle fibers induce rapid loss of force but not mass: implications for spinal bulbar muscular atrophy.

Authors: Kentaro Oki; Robert W Wiseman; S Marc Breedlove; Cynthia L Jordan
Journal: Muscle Nerve Date: 2013-04-30 Impact factor: 3.217

2. Neuromuscular junctions are pathological but not denervated in two mouse models of spinal bulbar muscular atrophy.

Authors: Jessica E Poort; Mary B Rheuben; S Marc Breedlove; Cynthia L Jordan
Journal: Hum Mol Genet Date: 2016-08-04 Impact factor: 6.150

3. Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA.

Authors: Katherine Halievski; Casey L Henley; Laurel Domino; Jessica E Poort; Martina Fu; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; S Marc Breedlove; Cynthia L Jordan
Journal: Exp Neurol Date: 2015-04-27 Impact factor: 5.330

4. Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.

Authors: Kayla J Renier; Sandra M Troxell-Smith; Jamie A Johansen; Masahisa Katsuno; Hiroaki Adachi; Gen Sobue; Jason P Chua; Hong Sun Kim; Andrew P Lieberman; S Marc Breedlove; Cynthia L Jordan
Journal: Endocrinology Date: 2014-04-17 Impact factor: 4.736

Administration of testosterone results in reversible deterioration in Kennedy's disease.

1. Androgen receptors in muscle fibers induce rapid loss of force but not mass: implications for spinal bulbar muscular atrophy.

2. Neuromuscular junctions are pathological but not denervated in two mouse models of spinal bulbar muscular atrophy.

3. Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA.

4. Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.

Review 5. Sex steroid-related candidate genes in psychiatric disorders.

Review 6. Inhibition of the Androgen Receptor by Antiandrogens in Spinobulbar Muscle Atrophy.

Review 7. Spinal and bulbar muscular atrophy: a motoneuron or muscle disease?

Review 8. Androgen receptor and Kennedy disease/spinal bulbar muscular atrophy.

9. Testosterone treatment fails to accelerate disease in a transgenic mouse model of spinal and bulbar muscular atrophy.

Review 10. New routes to therapy for spinal and bulbar muscular atrophy.