Literature DB >> 17055604

Dosimetric pre-treatment verification of IMRT using an EPID; clinical experience.

Mathilda van Zijtveld1, Maarten L P Dirkx, Hans C J de Boer, Ben J M Heijmen.   

Abstract

BACKGROUND AND
PURPOSE: In our clinic a QA program for IMRT verification, fully based on dosimetric measurements with electronic portal imaging devices (EPID), has been running for over 3 years. The program includes a pre-treatment dosimetric check of all IMRT fields. During a complete treatment simulation at the linac, a portal dose image (PDI) is acquired with the EPID for each patient field and compared with a predicted PDI. In this paper, the results of this pre-treatment procedure are analysed, and intercepted errors are reported. An automated image analysis procedure is proposed to limit the number of fields that need human intervention in PDI comparison.
MATERIALS AND METHODS: Most of our analyses are performed using the gamma index with 3% local dose difference and 3mm distance to agreement as reference values. Scalar parameters are derived from the gamma values to summarize the agreement between measured and predicted 2D PDIs. Areas with all pixels having gamma values larger than one are evaluated, making decisions based on clinically relevant criteria more straightforward.
RESULTS: In 270 patients, the pre-treatment checks revealed four clinically relevant errors. Calculation of statistics for a group of 75 patients showed that the patient-averaged mean gamma value inside the field was 0.43 +/- 0.13 (1SD) and only 6.1 +/- 6.8% of pixels had a gamma value larger than one. With the proposed automated image analysis scheme, visual inspection of images can be avoided in 2/3 of the cases.
CONCLUSION: EPIDs may be used for high accuracy and high resolution routine verification of IMRT fields to intercept clinically relevant dosimetric errors prior to the start of treatment. For the majority of fields, PDI comparison can fully rely on an automated procedure, avoiding excessive workload.

Entities:  

Mesh:

Year:  2006        PMID: 17055604     DOI: 10.1016/j.radonc.2006.09.008

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  13 in total

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Authors:  A J Vinall; A J Williams; V E Currie; A Van Esch; D Huyskens
Journal:  Br J Radiol       Date:  2010-11       Impact factor: 3.039

2.  A fully electronic intensity-modulated radiation therapy quality assurance (IMRT QA) process implemented in a network comprised of independent treatment planning, record and verify, and delivery systems.

Authors:  Daniel W Bailey; Lalith Kumaraswamy; Matthew B Podgorsak
Journal:  Radiol Oncol       Date:  2010-05-24       Impact factor: 2.991

3.  Implementation and validation of a commercial portal dosimetry software for intensity-modulated radiation therapy pre-treatment verification.

Authors:  C Varatharaj; Eugenia Moretti; M Ravikumar; Maria Rosa Malisan; Sanjay S Supe; Renato Padovani
Journal:  J Med Phys       Date:  2010-10

4.  Accurate IMRT fluence verification for prostate cancer patients using 'in-vivo' measured EPID images and in-room acquired kilovoltage cone-beam CT scans.

Authors:  Ali Sam Ali; Maarten L P Dirkx; Ruud M Cools; Ben J M Heijmen
Journal:  Radiat Oncol       Date:  2013-09-10       Impact factor: 3.481

5.  Impact of dose rate on accuracy of intensity modulated radiation therapy plan delivery using the pretreatment portal dosimetry quality assurance and setting up the workflow at hospital levels.

Authors:  Karunakaran Kaviarasu; N Arunai Nambi Raj; K Krishna Murthy; A Ananda Giri Babu; Bhaskar Laxman Durga Prasad
Journal:  J Med Phys       Date:  2015 Oct-Dec

6.  Feasibility of using two-dimensional array dosimeter for in vivo dose reconstruction via transit dosimetry.

Authors:  Heeteak Chung; Jonathan Li; Sanjiv Samant
Journal:  J Appl Clin Med Phys       Date:  2011-04-08       Impact factor: 2.102

7.  EPID dosimetry for pretreatment quality assurance with two commercial systems.

Authors:  Daniel W Bailey; Lalith Kumaraswamy; Mohammad Bakhtiari; Harish K Malhotra; Matthew B Podgorsak
Journal:  J Appl Clin Med Phys       Date:  2012-07-05       Impact factor: 2.102

8.  Portal dosimetry for pretreatment verification of IMRT plan: a comparison with 2D ion chamber array.

Authors:  Dayananda Shamurailatpam Sharma; Vaibav Mhatre; Malhotra Heigrujam; Kaustav Talapatra; Suman Mallik
Journal:  J Appl Clin Med Phys       Date:  2010-08-19       Impact factor: 2.102

9.  Acrylonitrile Butadiene Styrene (ABS) plastic based low cost tissue equivalent phantom for verification dosimetry in IMRT.

Authors:  Rajesh Kumar; S D Sharma; Sudesh Deshpande; Yogesh Ghadi; V S Shaiju; H I Amols; Y S Mayya
Journal:  J Appl Clin Med Phys       Date:  2009-12-17       Impact factor: 2.102

10.  Establishing action levels for EPID-based QA for IMRT.

Authors:  Rebecca M Howell; Iris P N Smith; Christie S Jarrio
Journal:  J Appl Clin Med Phys       Date:  2008-06-23       Impact factor: 2.102

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