Literature DB >> 17055556

Assessment of pretest probability of pulmonary embolism in the emergency department by physicians in training using the Wells model.

Andrea Penaloza1, Christian Mélot, Emmanuelle Dochy, Didier Blocklet, Pierre Alain Gevenois, Jean-Claude Wautrecht, Philippe Lheureux, Serge Motte.   

Abstract

INTRODUCTION: Assessment of pretest probability should be the initial step in investigation of patients with suspected pulmonary embolism (PE). In teaching hospitals physicians in training are often the first physicians to evaluate patients.
OBJECTIVE: To evaluate the accuracy of pretest probability assessment of PE by physicians in training using the Wells clinical model and to assess the safety of a diagnostic strategy including pretest probability assessment. PATIENTS AND METHODS: 291 consecutive outpatients with clinical suspicion of PE were categorized as having a low, moderate or high pretest probability of PE by physicians in training who could take supervising physicians' advice when they deemed necessary. Then, patients were managed according to a sequential diagnostic algorithm including D-dimer testing, lung scan, leg compression ultrasonography and helical computed tomography. Patients in whom PE was deemed absent were followed up for 3 months.
RESULTS: 34 patients (18%) had PE. Prevalence of PE in the low, moderate and high pretest probability groups categorized by physicians in training alone was 3% (95% confidence interval (CI): 1% to 9%), 31% (95% CI: 22% to 42%) and 100% (95% CI: 61% to 100%) respectively. One of the 152 untreated patients (0.7%, 95% CI: 0.1% to 3.6%) developed a thromboembolic event during the 3-month follow-up period.
CONCLUSION: Physicians in training can use the Wells clinical model to determine pretest probability of PE. A diagnostic strategy including the use of this model by physicians in training with access to supervising physicians' advice appears to be safe.

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Year:  2006        PMID: 17055556     DOI: 10.1016/j.thromres.2006.09.001

Source DB:  PubMed          Journal:  Thromb Res        ISSN: 0049-3848            Impact factor:   3.944


  4 in total

1.  Excluding pulmonary embolism in primary care using the Wells-rule in combination with a point-of care D-dimer test: a scenario analysis.

Authors:  Wim A M Lucassen; Renée A Douma; Diane B Toll; Harry R Büller; Henk C P M van Weert
Journal:  BMC Fam Pract       Date:  2010-09-13       Impact factor: 2.497

2.  Clinical and echocardiographic findings of patients with suspected acute pulmonary thromboembolism who underwent computed tomography pulmonary angiography.

Authors:  Atoosa Adibi; Shadi Nouri; Maryam Moradi; Javad Shahabi
Journal:  J Res Med Sci       Date:  2016-11-07       Impact factor: 1.852

3.  A case of monoclonal gammopathy of undetermined significance and minimal change disease complicated by bilateral pulmonary emboli.

Authors:  Thanuja Neerukonda; Alexandra Witt; Arsen Tan; Bilal Farooqi; Yasna Chaudhary; Christina Kovacs; Luis Silva
Journal:  SAGE Open Med Case Rep       Date:  2022-08-12

4.  Computed Tomography Angiography in Patients Evaluated for Acute Pulmonary Embolism with Low Serum D-dimer Levels: A Prospective Study.

Authors:  Lana Hirai Gimber; R Ing Travis; Jayme M Takahashi; Torrey L Goodman; Hyo-Chun Yoon
Journal:  Perm J       Date:  2009
  4 in total

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