| Literature DB >> 17055423 |
Tim Elliott1, Jacques Neefjes.
Abstract
The loading of peptides into the groove of MHC class I molecules prior to antigen presentation is a complex process. In this issue of Cell, Park et al. (2006) show that peptide loading gets a helping hand from a resident ER enzyme called protein disulfide isomerase, a chaperone that has oxidoreductase activity.Mesh：
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Year: 2006 PMID： 17055423 DOI： 10.1016/j.cell.2006.10.001
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582