Literature DB >> 17055148

Ligand-selective determinants in gonadotropin receptors.

J Bogerd1.   

Abstract

In mammals, the interactions between gonadotropins and their cognate receptors are highly specific; unintended cross-reactivity under normal physiological conditions has not been observed. This paper summarizes the comparative structure-function studies that aim at elucidating the molecular basis of the ligand selectivity.

Mesh：

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Year:  2006        PMID： 17055148     DOI： 10.1016/j.mce.2006.01.019

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  12 in total

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3.  Functional differences of invariant and highly conserved residues in the extracellular domain of the glycoprotein hormone receptors.

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Review 4.  Current concepts of follicle-stimulating hormone receptor gene regulation.

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6.  Dominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys.

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7.  Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor.

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9.  Trafficking of the follitropin receptor.

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Review 10.  Multiple facets of follicle-stimulating hormone receptor function.

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