Literature DB >> 17053400

False-positive axillary lymph node on FDG-PET/CT scan resulting from immunization.

Gethin Williams1, Robin M Joyce, J Anthony Parker.   

Abstract

An initial CT of a 59-year-old man with increasing back pain and weight loss showed lymphadenopathy in multiple nodal beds. A biopsy showed diffuse, large B-cell lymphoma (DLBCL). After initial chemotherapy, residual disease prompted an autologous stem cell transplant. After a follow-up FDG-PET/CT scan showed no FDG-avid disease, a subsequent study showed FDG uptake in a nonenlarged left axillary lymph node. Questioning elicited a recent immunization history. A follow-up PET/CT scan showed no uptake in this lymph node and no disease recurrence. Without this history, an unnecessary biopsy or treatment may have ensued. Methods to avoid such occurrences are discussed.

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Year:  2006        PMID： 17053400     DOI： 10.1097/01.rlu.0000242693.69039.70

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  13 in total

1.  (18)F-FDG uptake at vaccination site.

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2.  FDG uptake in axillary lymph nodes after vaccination against pandemic (H1N1).

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Journal:  Eur Radiol       Date:  2010-02-26       Impact factor: 5.315

3.  Duration of 18F-FDG avidity in lymph nodes after pandemic H1N1v and seasonal influenza vaccination.

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Journal:  Eur J Nucl Med Mol Imaging       Date:  2011-02-22       Impact factor: 9.236

4.  Systemic Immune Response to Vaccination on FDG-PET/CT.

Authors:  Mark Mingos; Stephanie Howard; Nicholas Giacalone; David Kozono; Heather Jacene
Journal:  Nucl Med Mol Imaging       Date:  2015-12-09

Review 5.  Role of modern imaging techniques for diagnosis of infection in the era of 18F-fluorodeoxyglucose positron emission tomography.

Authors:  Rakesh Kumar; Sandip Basu; Drew Torigian; Vivek Anand; Hongming Zhuang; Abass Alavi
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

6.  Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients.

Authors:  Simone M Goldinger; Reinhard Dummer; Petra Baumgaertner; Daniela Mihic-Probst; Katrin Schwarz; Anya Hammann-Haenni; Joerg Willers; Christine Geldhof; John O Prior; Thomas M Kündig; Olivier Michielin; Martin F Bachmann; Daniel E Speiser
Journal:  Eur J Immunol       Date:  2012-08-28       Impact factor: 5.532

7.  F18 fluorodeoxyglucose uptake in progressive transformation of germinal centres.

Authors:  B Rehani; Y Dowdy; A Bharija; P Strohmeyer
Journal:  Biomed Imaging Interv J       Date:  2008-01-01

8.  Generalized Lymph Node Activation after Influenza Vaccination on 18F FDG-PET/CT Imaging, an Important Pitfall in PET Interpretation.

Authors:  Narjess Ayati; Sarah Jesudason; Salvatore U Berlangieri; Andrew M Scott
Journal:  Asia Ocean J Nucl Med Biol       Date:  2017

9.  COVID-19 vaccine-related lymph node activation - patterns of uptake on PET-CT.

Authors:  Sweni Shah; Thomas Wagner; Malavika Nathan; Teresa Szyszko
Journal:  BJR Case Rep       Date:  2021-04-20

10.  New axillary lymph nodal F-18 fluoro-deoxy glucose uptake in an interim positron emission tomography scan - not always a sign of disease progression.

Authors:  Kuruva Manohar; Kanhaiyalal Agrawal; Anish Bhattacharya; Bhagwant Rai Mittal
Journal:  Indian J Nucl Med       Date:  2011-10
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