Literature DB >> 17052198

Regulation of purine nucleotide biosynthesis: in yeast and beyond.

R J Rolfes1.   

Abstract

Purine nucleotides are critically important for the normal functioning of cells due to their myriad of activities. It is important for cells to maintain a balance in the pool sizes of the adenine-containing and guanine-containing nucleotides, which occurs by a combination of de novo synthesis and salvage pathways that interconvert the purine nucleotides. This review describes the mechanism for regulation of the biosynthetic genes in the yeast Saccharomyces cerevisiae and compares this mechanism with that described in several microbial species.

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Year:  2006        PMID： 17052198     DOI： 10.1042/BST0340786

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  25 in total

1.  Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp.

Authors:  Brent W Anderson; Aili Hao; Kenneth A Satyshur; James L Keck; Jue D Wang
Journal:  J Mol Biol       Date:  2020-05-21       Impact factor: 5.469

2.  Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.

Authors:  Diego Iglesias-Gato; Pilar Martín-Marcos; María A Santos; Alan G Hinnebusch; Mercedes Tamame
Journal:  Genetics       Date:  2010-10-26       Impact factor: 4.562

3.  A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion.

Authors:  Joo Y Hong; Vidhu Mathur; Susan W Liebman
Journal:  Yeast       Date:  2011-05-18       Impact factor: 3.239

4.  Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice.

Authors:  Sélène Ferrari; Maurizio Sanguinetti; Flavia De Bernardis; Riccardo Torelli; Brunella Posteraro; Patrick Vandeputte; Dominique Sanglard
Journal:  Antimicrob Agents Chemother       Date:  2011-02-14       Impact factor: 5.191

5.  Activation of the ADE genes requires the chromatin remodeling complexes SAGA and SWI/SNF.

Authors:  Rebecca N Koehler; Nicole Rachfall; Ronda J Rolfes
Journal:  Eukaryot Cell       Date:  2007-06-15

6.  A microarray-based genetic screen for yeast chronological aging factors.

Authors:  Mirela Matecic; Daniel L Smith; Xuewen Pan; Nazif Maqani; Stefan Bekiranov; Jef D Boeke; Jeffrey S Smith
Journal:  PLoS Genet       Date:  2010-04-22       Impact factor: 5.917

7.  Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.

Authors:  Drew Stenesen; Jae Myoung Suh; Jin Seo; Kweon Yu; Kyu-Sun Lee; Jong-Seok Kim; Kyung-Jin Min; Jonathan M Graff
Journal:  Cell Metab       Date:  2013-01-08       Impact factor: 27.287

8.  Biological sex and DNA repair deficiency drive Alzheimer's disease via systemic metabolic remodeling and brain mitochondrial dysfunction.

Authors:  Tyler G Demarest; Vijay R Varma; Darlene Estrada; Mansi Babbar; Sambuddha Basu; Uma V Mahajan; Ruin Moaddel; Deborah L Croteau; Madhav Thambisetty; Mark P Mattson; Vilhelm A Bohr
Journal:  Acta Neuropathol       Date:  2020-04-24       Impact factor: 17.088

9.  Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines.

Authors:  Maureen McKeague; Yen-Hsiang Wang; Aaron Cravens; Maung Nyan Win; Christina D Smolke
Journal:  Metab Eng       Date:  2016-08-09       Impact factor: 9.783

10.  The new yeast is a mouse.

Authors:  Rhona H Borts
Journal:  PLoS Biol       Date:  2009-05-05       Impact factor: 8.029
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