Literature DB >> 17052171

The role of myosin Va in secretory granule trafficking and exocytosis.

T W Eichler1, T Kögel, N V Bukoreshtliev, H-H Gerdes.   

Abstract

It emerges that myosin Va plays multiple roles in the trafficking of SGs (secretory granules). In addition to a function in the capture and transport of newly formed SGs in the F-actin-rich cortex, myosin Va is implicated in late transport events of these organelles, which precede their exocytosis. Consistent with these roles, interactions of myosin Va with an array of well-known proteins involved in regulated protein secretion have been documented.

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Year:  2006        PMID: 17052171     DOI: 10.1042/BST0340671

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN: 0300-5127            Impact factor:   5.407


  24 in total

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