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Literature DB >> 17051198

Structural biology: enzyme target to latch on to.

Malcolm A Leissring, Dennis J Selkoe.

Abstract

Mesh：

Substances：
Insulin
Insulysin

Year: 2006 PMID： 17051198 DOI： 10.1038/nature05210

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

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14 in total

Review 1. Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin.

Authors: E Malito; R E Hulse; W-J Tang
Journal: Cell Mol Life Sci Date: 2008-08 Impact factor: 9.261

Review 2. Inhibition of Insulin Degrading Enzyme to Control Diabetes Mellitus and its Applications on some Other Chronic Disease: a Critical Review.

Authors: Md Shofiul Azam; Md Wahiduzzaman; Md Reyad-Ul-Ferdous; Md Nahidul Islam; Mukta Roy
Journal: Pharm Res Date: 2022-04-04 Impact factor: 4.200

3. A capillary electrophoresis method for evaluation of Abeta proteolysis in vitro.

Authors: Benjamin J Alper; Walter K Schmidt
Journal: J Neurosci Methods Date: 2008-11-21 Impact factor: 2.390

4. Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.

Authors: Malcolm A Leissring; Enrico Malito; Sabrine Hedouin; Lael Reinstatler; Tomoko Sahara; Samer O Abdul-Hay; Shakeel Choudhry; Ghulam M Maharvi; Abdul H Fauq; Malwina Huzarska; Philip S May; Sungwoon Choi; Todd P Logan; Benjamin E Turk; Lewis C Cantley; Marika Manolopoulou; Wei-Jen Tang; Ross L Stein; Gregory D Cuny; Dennis J Selkoe
Journal: PLoS One Date: 2010-05-07 Impact factor: 3.240

5. Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme.

Authors: Giuseppe Grasso; Ashley I Bush; Roberta D'Agata; Enrico Rizzarelli; Giuseppe Spoto
Journal: Eur Biophys J Date: 2008-12-02 Impact factor: 1.733

10. Development and Characterization of Quantitative, High-Throughput-Compatible Assays for Proteolytic Degradation of Glucagon.

Authors: Caitlin N Suire; Shelley Lane; Malcolm A Leissring
Journal: SLAS Discov Date: 2018-07-11 Impact factor: 3.341

Structural biology: enzyme target to latch on to.

Review 1. Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin.

Review 2. Inhibition of Insulin Degrading Enzyme to Control Diabetes Mellitus and its Applications on some Other Chronic Disease: a Critical Review.

3. A capillary electrophoresis method for evaluation of Abeta proteolysis in vitro.

4. Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.

5. Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme.

6. Glucose inhibits the insulin-induced activation of the insulin-degrading enzyme in HepG2 cells.

Review 7. Targeting Insulin-Degrading Enzyme in Insulin Clearance.

8. Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening.

9. Insulin-degrading enzyme is exported via an unconventional protein secretion pathway.

10. Development and Characterization of Quantitative, High-Throughput-Compatible Assays for Proteolytic Degradation of Glucagon.