Literature DB >> 17050810

Presence of the exoU gene of Pseudomonas aeruginosa is correlated with cytotoxicity in MDCK cells but not with colonization in BALB/c mice.

Hsi-Hsun Lin1, Shiao-ping Huang, Hsiu-Chen Teng, Dar-Der Ji, Yao-Shen Chen, Ya-Lei Chen.   

Abstract

A total of 141 independent strains of Pseudomonas aeruginosa with different heterogeneities in the exo gene (exoS, exoT, exoU, and exoY) background were examined for their pathogenic roles. Results indicated that the exoU gene is the major contributor to cytotoxicity in Madin-Darby canine kidney cells but is not related to bacterial colonization in mice.

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Year:  2006        PMID： 17050810      PMCID： PMC1698386          DOI： 10.1128/JCM.01531-06

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  13 in total

1.  Evaluation of random amplified polymorphic DNA typing of Pseudomonas aeruginosa.

Authors:  M Campbell; E Mahenthiralingam; D P Speert
Journal:  J Clin Microbiol       Date:  2000-12       Impact factor: 5.948

2.  ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury.

Authors:  V Finck-Barbançon; J Goranson; L Zhu; T Sawa; J P Wiener-Kronish; S M Fleiszig; C Wu; L Mende-Mueller; D W Frank
Journal:  Mol Microbiol       Date:  1997-08       Impact factor: 3.501

3.  Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections.

Authors:  A Roy-Burman; R H Savel; S Racine; B L Swanson; N S Revadigar; J Fujimoto; T Sawa; D W Frank; J P Wiener-Kronish
Journal:  J Infect Dis       Date:  2001-05-17       Impact factor: 5.226

4.  Comparison of the exoS gene and protein expression in soil and clinical isolates of Pseudomonas aeruginosa.

Authors:  M W Ferguson; J A Maxwell; T S Vincent; J da Silva; J C Olson
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

5.  Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

Authors:  Alan R Hauser; Enesha Cobb; Maria Bodi; Dolors Mariscal; Jordi Vallés; Joanne N Engel; Jordi Rello
Journal:  Crit Care Med       Date:  2002-03       Impact factor: 7.598

6.  Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa.

Authors:  Heather Feltman; Grant Schulert; Salman Khan; Manu Jain; Lance Peterson; Alan R Hauser
Journal:  Microbiology       Date:  2001-10       Impact factor: 2.777

Review 7.  Targeting mechanisms of Pseudomonas aeruginosa pathogenesis.

Authors:  E Kipnis; T Sawa; J Wiener-Kronish
Journal:  Med Mal Infect       Date:  2006-01-19       Impact factor: 2.152

Review 8.  ExoU is a potent intracellular phospholipase.

Authors:  Hiromi Sato; Dara W Frank
Journal:  Mol Microbiol       Date:  2004-09       Impact factor: 3.501

9.  Genotypic and phenotypic analysis of type III secretion system in a cohort of Pseudomonas aeruginosa bacteremia isolates: evidence for a possible association between O serotypes and exo genes.

Authors:  Philippe Berthelot; Ina Attree; Patrick Plésiat; Jacqueline Chabert; Sophie de Bentzmann; Bruno Pozzetto; Florence Grattard
Journal:  J Infect Dis       Date:  2003-07-23       Impact factor: 5.226

10.  Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia.

Authors:  Grant S Schulert; Heather Feltman; Shira D P Rabin; Ciara G Martin; Scott E Battle; Jordi Rello; Alan R Hauser
Journal:  J Infect Dis       Date:  2003-11-21       Impact factor: 5.226
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  5 in total

1.  Label-Free Quantitative Proteomics Distinguishes General and Site-Specific Host Responses to Pseudomonas aeruginosa Infection at the Ocular Surface.

Authors:  Jason Yeung; Mihaela Gadjeva; Jennifer Geddes-McAlister
Journal:  Proteomics       Date:  2020-01-07       Impact factor: 3.984

2.  The use of nanoscale visible light-responsive photocatalyst TiO2-Pt for the elimination of soil-borne pathogens.

Authors:  Ya-Lei Chen; Yao-Shen Chen; Hao Chan; Yao-Hsuan Tseng; Shu-Ru Yang; Hsin-Ying Tsai; Hong-Yi Liu; Der-Shan Sun; Hsin-Hou Chang
Journal:  PLoS One       Date:  2012-02-22       Impact factor: 3.240

3.  Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.

Authors:  Alexander Belyy; Dorothée Raoux-Barbot; Cosmin Saveanu; Abdelkader Namane; Vasily Ogryzko; Lina Worpenberg; Violaine David; Veronique Henriot; Souad Fellous; Christien Merrifield; Elodie Assayag; Daniel Ladant; Louis Renault; Undine Mechold
Journal:  Nat Commun       Date:  2016-12-05       Impact factor: 14.919

4.  Characterization of Three Ocular Clinical Isolates of P. aeruginosa: Viability, Biofilm Formation, Adherence, Infectivity, and Effects of Glycyrrhizin.

Authors:  Xudong Peng; Sandamali A Ekanayaka; Sharon A McClellan; Ronald P Barrett; Kerry Vistisen; Linda D Hazlett
Journal:  Pathogens       Date:  2017-10-24

5.  Pseudomonas aeruginosa population structure revisited.

Authors:  Jean-Paul Pirnay; Florence Bilocq; Bruno Pot; Pierre Cornelis; Martin Zizi; Johan Van Eldere; Pieter Deschaght; Mario Vaneechoutte; Serge Jennes; Tyrone Pitt; Daniel De Vos
Journal:  PLoS One       Date:  2009-11-13       Impact factor: 3.240
  5 in total

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