Literature DB >> 17050181

New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum.

Canjun Li1, Yiming Li, Hao H Sun.   

Abstract

Two new lanostanoids, 7-oxo-ganoderic acid Z (1) and 15-hydroxy-ganoderic acid S (2), were isolated from a lipophilic extract of the fruiting body of Ganoderma lucidum. The structures of both compounds were established by interpretation of their spectroscopic data. Compounds 1 and 2 both exhibited inhibitory activities against the HMG-CoA reductase and acyl CoA acyltransferase.

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Year:  2006        PMID： 17050181     DOI： 10.1080/14786410600921466

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  4 in total

1.  Apoptotic and Immune Restoration Effects of Ganoderic Acids Define a New Prospective for Complementary Treatment of Cancer.

Authors:  Faisal F Y Radwan; J Manuel Perez; Azizul Haque
Journal:  J Clin Cell Immunol       Date:  2011-12-11

Review 2.  Accessing biological actions of Ganoderma secondary metabolites by in silico profiling.

Authors:  Ulrike Grienke; Teresa Kaserer; Florian Pfluger; Christina E Mair; Thierry Langer; Daniela Schuster; Judith M Rollinger
Journal:  Phytochemistry       Date:  2014-11-06       Impact factor: 4.072

3.  Ganoderic acid A ameliorates non-alcoholic streatohepatitis (NASH) induced by high-fat high-cholesterol diet in mice.

Authors:  Jing Zhu; Jiexia Ding; Siying Li; Jie Jin
Journal:  Exp Ther Med       Date:  2022-02-24       Impact factor: 2.447

4.  Development of a rapid and confirmatory method to identify ganoderic acids in ganoderma mushrooms.

Authors:  Ying Qi; Lingling Zhao; Hao H Sun
Journal:  Front Pharmacol       Date:  2012-05-07       Impact factor: 5.810
  4 in total

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