| Literature DB >> 17047685 |
Matthew V Rockman1, Leonid Kruglyak.
Abstract
A new field of genetic analysis of global gene expression has emerged in recent years, driven by the realization that traditional techniques of linkage and association analysis can be applied to thousands of transcript levels measured by microarrays. Genetic dissection of transcript abundance has shed light on the architecture of quantitative traits, provided a new approach for connecting DNA sequence variation with phenotypic variation, and improved our understanding of transcriptional regulation and regulatory variation.Mesh：
Substances：
Year: 2006 PMID： 17047685 DOI： 10.1038/nrg1964
Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242