Literature DB >> 1704751

A search for longitudinal variations in trace element levels in nails of Alzheimer's disease patients.

D E Vance1, W D Ehmann, W R Markesbery.   

Abstract

Levels of Br, Hg, K, and Zn were determined by INAA in the nails of Alzheimer's disease (AD) patients at 6-mo intervals for up to 3 yr. These elements have been shown to be imbalanced in AD nail. Bromine showed no trends. Mercury tended to decrease in nail with increasing age of patient, and with the duration and severity of the dementia. Potassium and Zn tended to increase with these same factors. Hence, progressive changes in trace-element levels do occur in AD nail, although imbalances are detected even in the earliest sampled stages of the disease.

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Year:  1990        PMID： 1704751     DOI： 10.1007/bf02992701

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  13 in total

1.  Trace element content in fingernails and hair of a nonindustrialized US control population.

Authors:  D E Vance; W D Ehmann; W R Markesbery
Journal:  Biol Trace Elem Res       Date:  1988 Sep-Dec       Impact factor: 3.738

2.  Longitudinal studies of regional cerebral metabolism in Alzheimer's disease.

Authors:  W J Jagust; R P Friedland; T F Budinger; E Koss; B Ober
Journal:  Neurology       Date:  1988-06       Impact factor: 9.910

3.  Alzheimer's disease: advances in basic research and therapies.

Authors:  A Cronin-Golomb
Journal:  Neuropsychologia       Date:  1988       Impact factor: 3.139

4.  Altered glucose metabolism in fibroblasts from patients with Alzheimer's disease.

Authors:  N R Sims; J M Finegan; J P Blass
Journal:  N Engl J Med       Date:  1985-09-05       Impact factor: 91.245

5.  Blood acetyl- and butyrylcholinesterases in senile dementia of Alzheimer type.

Authors:  J R Atack; E K Perry; R H Perry; I D Wilson; M J Bober; G Blessed; B E Tomlinson
Journal:  J Neurol Sci       Date:  1985-08       Impact factor: 3.181

6.  Bone mineral content of the lumbar spine in normal and osteoporotic women: cross-sectional and longitudinal studies.

Authors:  B Krølner; S Pors Nielsen
Journal:  Clin Sci (Lond)       Date:  1982-03       Impact factor: 6.124

7.  Platelet membrane fluidity in Alzheimer's disease and major depression.

Authors:  G S Zubenko; B M Cohen; C F Reynolds; F Boller; I Malinakova; N Keefe
Journal:  Am J Psychiatry       Date:  1987-07       Impact factor: 18.112

8.  Trace element imbalances in hair and nails of Alzheimer's disease patients.

Authors:  D E Vance; W D Ehmann; W R Markesbery
Journal:  Neurotoxicology       Date:  1988       Impact factor: 4.294

9.  Regional brain trace-element studies in Alzheimer's disease.

Authors:  C M Thompson; W R Markesbery; W D Ehmann; Y X Mao; D E Vance
Journal:  Neurotoxicology       Date:  1988       Impact factor: 4.294

10.  Mild senile dementia of the Alzheimer type: 2. Longitudinal assessment.

Authors:  L Berg; J P Miller; M Storandt; J Duchek; J C Morris; E H Rubin; W J Burke; L A Coben
Journal:  Ann Neurol       Date:  1988-05       Impact factor: 10.422
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  2 in total

1.  Impaired peripheral zinc metabolism in patients with senile dementia of probable Alzheimer's type as shown by low plasma concentrations of thymulin.

Authors:  F Licastro; L J Davis; E Mocchegiani; N Fabris
Journal:  Biol Trace Elem Res       Date:  1996-01       Impact factor: 3.738

2.  Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid.

Authors:  Blaine R Roberts; James D Doecke; Alan Rembach; L Fernanda Yévenes; Christopher J Fowler; Catriona A McLean; Monica Lind; Irene Volitakis; Colin L Masters; Ashley I Bush; Dominic J Hare
Journal:  Acta Neuropathol Commun       Date:  2016-11-14       Impact factor: 7.801
  2 in total

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