PRIMARY OBJECTIVE: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). RESEARCH DESIGN: Case-control study. METHODS AND PROCEDURES: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). MAIN OUTCOME AND RESULTS: The amount of TCI was significantly lower in the patients than the control subjects (p < 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787, p < 0.001). CONCLUSION: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.
PRIMARY OBJECTIVE: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). RESEARCH DESIGN: Case-control study. METHODS AND PROCEDURES: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). MAIN OUTCOME AND RESULTS: The amount of TCI was significantly lower in the patients than the control subjects (p < 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787, p < 0.001). CONCLUSION: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.
Authors: Asli Demirtas-Tatlidede; Andrew M Vahabzadeh-Hagh; Montserrat Bernabeu; Jose M Tormos; Alvaro Pascual-Leone Journal: J Head Trauma Rehabil Date: 2012 Jul-Aug Impact factor: 2.710
Authors: Jonathan A N Fisher; Stanley Huang; Meijun Ye; Marjan Nabili; W Bryan Wilent; Victor Krauthamer; Matthew R Myers; Cristin G Welle Journal: IEEE Trans Neural Syst Rehabil Eng Date: 2016-03-01 Impact factor: 4.528