Intake and circulating concentrations of antioxidants in metabolic syndrome.

Metabolic syndrome, which occurs commonly in populations around the world, has been associated with an increased risk for developing cardiovascular disease and diabetes. Oxidative stress, which has been implicated in the pathogenesis of cardiovascular disease and diabetes, is a common feature of metabolic syndrome. Limited evidence suggests that circulating concentrations of antioxidants are decreased among people with metabolic syndrome. The contributions of reduced consumption and increased utilization of antioxidants leading to increased oxidative stress are largely unknown. People with metabolic syndrome appear to be an attractive group for future research about possible therapeutic options of antioxidants in the medical management of this syndrome.