Literature DB >> 17044802

The safety of anidulafungin.

José A Vazquez1.   

Abstract

The echinocandins are a new class of antifungal that have shown promising results in treating a variety of fungal infections. Anidulafungin is the newest approved echinocandin and may have some advantages over existing antifungals. It has activity against a broad range of fungi. It is unique because it undergoes a process of slow chemical degradation rather than being metabolised. Studies evaluating the use of anidulafungin in combination with other commonly used drugs have not demonstrated any significant drug-drug interactions or adverse events. Thus far, anidulafungin appears to have an excellent safety profile with few adverse events. Based on early clinical experience, it appears that anidulafungin will be a valuable and safe asset in the management of serious and difficult-to-treat fungal infections.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17044802     DOI: 10.1517/14740338.5.6.751

Source DB:  PubMed          Journal:  Expert Opin Drug Saf        ISSN: 1474-0338            Impact factor:   4.250


  5 in total

1.  Conclusions. Anidulafungin is a new echinocandin developed for more effective treatment of serious systemic fungal infections.

Authors:  Pasquale De Bellis
Journal:  Drugs       Date:  2009       Impact factor: 9.546

2.  Combined therapy of voriconazole and anidulafungin in murine infections by Aspergillus flavus.

Authors:  Enrique Calvo; F Javier Pastor; Valentina Salas; Emilio Mayayo; Josep Guarro
Journal:  Mycopathologia       Date:  2011-12-04       Impact factor: 2.574

Review 3.  Pharmacokinetics, antifungal activity and clinical efficacy of anidulafungin in the treatment of fungal infections.

Authors:  Effie L Kuti; Joseph L Kuti
Journal:  Expert Opin Drug Metab Toxicol       Date:  2010-10       Impact factor: 4.481

Review 4.  Current perspectives on echinocandin class drugs.

Authors:  David S Perlin
Journal:  Future Microbiol       Date:  2011-04       Impact factor: 3.165

5.  Anidulafungin: an evidence-based review of its use in invasive fungal infections.

Authors:  Susan L Davis; Jose A Vazquez
Journal:  Core Evid       Date:  2008-07-31
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.