Literature DB >> 17044582

Crack cocaine causing fatal vasoconstriction of the aorta.

Joanne Williams1, Jonathan Wasserberger.   

Abstract

Cocaine is the most powerful central nervous stimulant found in nature. All forms of cocaine cause tachycardia and vasoconstriction. A smokable, rapidly reacting form of cocaine base, "crack," is highly addictive. Smoking crack introduces a high concentration of cocaine into the bloodstream, rendering it especially dangerous. We report a case that visually demonstrates severe aortic vasoconstriction from the suprarenal aorta and extending to both femoral arteries and beyond, resulting in renal failure and fatal bowel ischemia after a 5-day binge of crack cocaine.

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Year:  2006        PMID: 17044582     DOI: 10.1016/j.jemermed.2005.08.021

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  3 in total

1.  Behavioral and brain temperature responses to salient environmental stimuli and intravenous cocaine in rats: effects of diazepam.

Authors:  Eugene A Kiyatkin; David Bae
Journal:  Psychopharmacology (Berl)       Date:  2007-10-16       Impact factor: 4.530

2.  Behavioral and temperature effects of delta 9-tetrahydrocannabinol in human-relevant doses in rats.

Authors:  Michael S Smirnov; Eugene A Kiyatkin
Journal:  Brain Res       Date:  2008-06-26       Impact factor: 3.252

3.  Brain temperature responses to salient stimuli persist during dopamine receptor blockade despite a blockade of locomotor responses.

Authors:  Eugene A Kiyatkin
Journal:  Pharmacol Biochem Behav       Date:  2008-08-08       Impact factor: 3.533

  3 in total

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