Literature DB >> 17042387

Serum and urine concentrations of trypsinogen-activation peptide as markers for acute pancreatitis in cats.

Heidi S Allen1, Jörg Steiner, John Broussard, Caroline Mansfield, David A Williams, Boyd Jones.   

Abstract

The purpose of this study was to compare the clinical utility of the serum concentration of feline trypsin-like immunoreactivity (fTLI), the plasma and urine concentrations of trypsinogen-activation peptide (TAP), and the ratio of the urine TAP and creatinine concentrations (TAP:Cr) in the diagnosis of feline acute pancreatitis. We used 13 healthy cats and 10 cats with a diagnosis of acute pancreatitis. The mean serum fTLI and plasma TAP concentrations were significantly higher in the cats with acute pancreatitis than in the healthy cats (P < 0.05); the mean urine TAP concentrations and the median urine TAP:Cr ratios were not significantly different. Among the cats examined in this study, there was no benefit of plasma TAP over serum fTLI in the evaluation of suspected acute pancreatitis.

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Year:  2006        PMID: 17042387      PMCID: PMC1562539     

Source DB:  PubMed          Journal:  Can J Vet Res        ISSN: 0830-9000            Impact factor:   1.310


  10 in total

1.  Development and validation of an enzyme-linked immunosorbent assay for feline trypsin-like immunoreactivity.

Authors:  J M Steiner; D A Williams; E M Moeller; T Melgarejo
Journal:  Am J Vet Res       Date:  2000-06       Impact factor: 1.156

2.  Comparison of the sensitivity of different diagnostic tests for pancreatitis in cats.

Authors:  A Gerhardt; J M Steiner; D A Williams; S Kramer; C Fuchs; M Janthur; M Hewicker-Trautwein; I Nolte
Journal:  J Vet Intern Med       Date:  2001 Jul-Aug       Impact factor: 3.333

3.  Disagrees with criteria for diagnosing pancreatitis in cats.

Authors:  J M Steiner; D A Williams
Journal:  J Am Vet Med Assoc       Date:  2000-09-15       Impact factor: 1.936

4.  Evaluation of serum feline trypsin-like immunoreactivity for the diagnosis of pancreatitis in cats.

Authors:  N C Swift; S L Marks; N J MacLachlan; C R Norris
Journal:  J Am Vet Med Assoc       Date:  2000-07-01       Impact factor: 1.936

5.  Plasma and urinary trypsinogen activation peptide in healthy dogs, dogs with pancreatitis and dogs with other systemic diseases.

Authors:  C S Mansfield; B R Jones
Journal:  Aust Vet J       Date:  2000-06       Impact factor: 1.281

6.  Assessing the severity of canine pancreatitis.

Authors:  Caroline S Mansfield; Boyd R Jones; T Spillman
Journal:  Res Vet Sci       Date:  2003-04       Impact factor: 2.534

7.  Assay of trypsinogen activation in the cat experimental model of acute pancreatitis.

Authors:  N D Karanjia; A L Widdison; A Jehanli; J Hermon-Taylor; H A Reber
Journal:  Pancreas       Date:  1993-03       Impact factor: 3.327

8.  Generation and possible significance of trypsinogen activation peptides in experimental acute pancreatitis in the rat.

Authors:  C Fernández-del Castillo; J Schmidt; D W Rattner; K Lewandrowski; C C Compton; A Jehanli; G Patel; J Hermon-Taylor; A L Warshaw
Journal:  Pancreas       Date:  1992       Impact factor: 3.327

9.  Trypsinogen-activation peptides in experimental rat pancreatitis: prognostic implications and histopathologic correlates.

Authors:  J Schmidt; C Fernández-del Castillo; D W Rattner; K Lewandrowski; C C Compton; A L Warshaw
Journal:  Gastroenterology       Date:  1992-09       Impact factor: 22.682

10.  Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis.

Authors:  A M Gudgeon; D I Heath; P Hurley; A Jehanli; G Patel; C Wilson; A Shenkin; B M Austen; C W Imrie; J Hermon-Taylor
Journal:  Lancet       Date:  1990-01-06       Impact factor: 79.321

  10 in total
  2 in total

Review 1.  Laboratory tests for diagnosis of gastrointestinal and pancreatic diseases.

Authors:  Olivier Dossin
Journal:  Top Companion Anim Med       Date:  2011-05

2.  ACVIM consensus statement on pancreatitis in cats.

Authors:  Marnin A Forman; Joerg M Steiner; P Jane Armstrong; Melinda S Camus; Lorrie Gaschen; Steve L Hill; Caroline S Mansfield; Katja Steiger
Journal:  J Vet Intern Med       Date:  2021-02-15       Impact factor: 3.333

  2 in total

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