| Literature DB >> 17039453 |
M Daniel Givens1, Kay P Riddell, Yijing Zhang, Patricia K Galik, David A Stringfellow, Bruce W Brodersen, James A Jackson, Michael A Ellsworth, Martin D Ficken, Robert L Carson, James G W Wenzel, M Shonda Marley.
Abstract
A commercial vaccine containing modified-live bovine viral diarrhea virus (BVDV; types 1 and 2) was administered to one group of 22 peripubertal bulls 28 days before intranasal inoculation with a type 1 strain of BVDV. A second group of 23 peripubertal bulls did not receive the modified-live BVDV vaccine before intranasal inoculation. Ten of 23 unvaccinated bulls--but none of the vaccinated bulls--developed a persistent testicular infection as determined by immunohistochemistry and polymerase chain reaction. Results of this study indicate that administration of a modified-live vaccine containing BVDV can prevent persistent testicular infection if peripubertal bulls are vaccinated before viral exposure.Entities:
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Year: 2006 PMID： 17039453
Source DB: PubMed Journal: Vet Ther ISSN： 1528-3593