Literature DB >> 17039316

A pediatric patient with neuro-Behçet's disease.

Saori Hatachi1, Takashi Nakazawa, Akio Morinobu, Shinpei Kasagi, Yoshinori Kogata, Gohichi Kageyama, Seiji Kawano, Masahiro Koshiba, Shunichi Kumagai.   

Abstract

Behçet's disease is rare in childhood. We describe a 10-year-old boy with neuro-Behçet's disease (NB) who presented with fever, headache, vertigo, and hearing loss. An examination of the cerebrospinal fluid (CSF) revealed pleocytosis as well as elevated protein and interleukin (IL)-6 levels. Brain magnetic resonance imaging (MRI) showed hyperintensity of the right thalamus and midbrain on T2-WI, and gadolinium (Gd) enhancement of left acoustic nerve origin. HLA-B51 was positive. Prednisolone combined with methotrexate resulted in a complete remission. Brain MRI and the CSF IL-6 level were useful for the diagnosis and monitoring of this pediatric patient with NB.

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Year:  2006        PMID: 17039316     DOI: 10.1007/s10165-006-0507-1

Source DB:  PubMed          Journal:  Mod Rheumatol        ISSN: 1439-7595            Impact factor:   3.023


  3 in total

Review 1.  Vertigo and autoimmunity.

Authors:  Roberto Bovo; Andrea Ciorba; Alessandro Martini
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-10-16       Impact factor: 2.503

Review 2.  Advances in Biomarker-Guided Therapy for Pediatric- and Adult-Onset Neuroinflammatory Disorders: Targeting Chemokines/Cytokines.

Authors:  Michael R Pranzatelli
Journal:  Front Immunol       Date:  2018-04-04       Impact factor: 7.561

Review 3.  Neuro-Behçet's disease in childhood: a focus on the neuro-ophthalmological features.

Authors:  Paolo Mora; Chiara Menozzi; Jelka G Orsoni; Pierangela Rubino; Livia Ruffini; Arturo Carta
Journal:  Orphanet J Rare Dis       Date:  2013-01-29       Impact factor: 4.123

  3 in total

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