Literature DB >> 17039232

The downregulation of asparagine synthetase expression can increase the sensitivity of cells resistant to l-asparaginase.

B S Li, L J Gu, C Y Luo, W S Li, L M Jiang, S H Shen, H Jiang, S H Shen, B Zhang, J Chen, H L Xue, J Y Tang.   

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Year:  2006        PMID： 17039232     DOI： 10.1038/sj.leu.2404423

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  12 in total

1.  HAP1 loss confers l-asparaginase resistance in ALL by downregulating the calpain-1-Bid-caspase-3/12 pathway.

Authors:  Jung Kwon Lee; SungMyung Kang; Xidi Wang; Jesusa L Rosales; Xu Gao; Hee-Guk Byun; Yan Jin; Songbin Fu; Jinghua Wang; Ki-Young Lee
Journal:  Blood       Date:  2019-02-28       Impact factor: 22.113

2.  Epigenetic deregulation in pediatric acute lymphoblastic leukemia.

Authors:  Zac Chatterton; Leah Morenos; Francoise Mechinaud; David M Ashley; Jeffrey M Craig; Alexandra Sexton-Oates; Minhee S Halemba; Mandy Parkinson-Bates; Jane Ng; Debra Morrison; William L Carroll; Richard Saffery; Nicholas C Wong
Journal:  Epigenetics       Date:  2014-01-06       Impact factor: 4.528

3.  Asparagine synthetase is partially localized to the plasma membrane and upregulated by L-asparaginase in U937 cells.

Authors:  Yingyi He; Benshang Li; Changying Luo; Shuhong Shen; Jing Chen; Huiliang Xue; Jingyan Tang; Longjun Gu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-04-20

4.  Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.

Authors:  Elizabeth K Ruzzo; José-Mario Capo-Chichi; Bruria Ben-Zeev; David Chitayat; Hanqian Mao; Andrea L Pappas; Yuki Hitomi; Yi-Fan Lu; Xiaodi Yao; Fadi F Hamdan; Kimberly Pelak; Haike Reznik-Wolf; Ifat Bar-Joseph; Danit Oz-Levi; Dorit Lev; Tally Lerman-Sagie; Esther Leshinsky-Silver; Yair Anikster; Edna Ben-Asher; Tsviya Olender; Laurence Colleaux; Jean-Claude Décarie; Susan Blaser; Brenda Banwell; Rasesh B Joshi; Xiao-Ping He; Lysanne Patry; Rachel J Silver; Sylvia Dobrzeniecka; Mohammad S Islam; Abul Hasnat; Mark E Samuels; Dipendra K Aryal; Ramona M Rodriguiz; Yong-Hui Jiang; William C Wetsel; James O McNamara; Guy A Rouleau; Debra L Silver; Doron Lancet; Elon Pras; Grant A Mitchell; Jacques L Michaud; David B Goldstein
Journal:  Neuron       Date:  2013-10-16       Impact factor: 17.173

5.  Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo.

Authors:  Georg Karpel-Massler; Doruntina Ramani; Chang Shu; Marc-Eric Halatsch; Mike-Andrew Westhoff; Jeffrey N Bruce; Peter Canoll; Markus D Siegelin
Journal:  Oncotarget       Date:  2016-06-07

6.  Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines.

Authors:  Wei-Wen Chien; Céline Le Beux; Nicolas Rachinel; Michel Julien; Claire-Emmanuelle Lacroix; Soraya Allas; Pierre Sahakian; Aurélie Cornut-Thibaut; Loïc Lionnard; Jérôme Kucharczak; Abdel Aouacheria; Thierry Abribat; Gilles Salles
Journal:  Sci Rep       Date:  2015-01-28       Impact factor: 4.379

7.  Genome-wide loss-of-function genetic screening identifies opioid receptor μ1 as a key regulator of L-asparaginase resistance in pediatric acute lymphoblastic leukemia.

Authors:  S M Kang; J L Rosales; V Meier-Stephenson; S Kim; K Y Lee; A Narendran
Journal:  Oncogene       Date:  2017-06-26       Impact factor: 9.867

8.  Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine.

Authors:  Zhou Zhu; Nathan T Ihle; Paul A Rejto; Patrick P Zarrinkar
Journal:  BMC Genomics       Date:  2016-06-13       Impact factor: 3.969

9.  CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.

Authors:  Meng-Shian Chen; Sheng-Fan Wang; Chih-Yi Hsu; Pen-Hui Yin; Tien-Shun Yeh; Hsin-Chen Lee; Ling-Ming Tseng
Journal:  Oncotarget       Date:  2017-12-09

10.  Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro.

Authors:  Wen-Jian Liu; Hua Wang; Xiong-Wen Peng; Wei-da Wang; Na-Wei Liu; Yang Wang; Yue Lu
Journal:  Onco Targets Ther       Date:  2018-10-08       Impact factor: 4.147
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