Literature DB >> 17036234

[Significance of microbial colonisation in materials for orthopaedic technology. New insights].

F Kipp1, K Angermeier, A Koller, H H Wetz, C Hornberg.   

Abstract

A great problem in the treatment of diabetes are infections of diabetic feet. A likely reservoir of microorganisms are contaminated orthopaedic materials. Insoles from 70 patients were examined for potential microbial colonisation. Commonly employed materials were contaminated in vitro under standardised conditions using known microorganisms. After treating with an alcoholic skin disinfectant, the organisms were counted semiquantitatively. In addition to pathogens, the surfaces showed mainly microorganisms present in the normal skin flora. In all materials tested, disinfection reduced the number of organisms by 4-5 log orders. It could be shown that simple disinfection (wiping) reduces the microorganisms present on orthopaedic materials to an acceptable number. Further studies are needed to determine whether this also reduces the incidence of diabetic skin and soft tissue infection.

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Year:  2006        PMID: 17036234     DOI: 10.1007/s00132-006-1012-0

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  17 in total

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Authors:  William J Jeffcoate; Keith G Harding
Journal:  Lancet       Date:  2003-05-03       Impact factor: 79.321

2.  Diagnosis and treatment of diabetic foot infections.

Authors:  Benjamin A Lipsky; Anthony R Berendt; H Gunner Deery; John M Embil; Warren S Joseph; Adolf W Karchmer; Jack L LeFrock; Daniel P Lew; Jon T Mader; Carl Norden; James S Tan
Journal:  Clin Infect Dis       Date:  2004-09-10       Impact factor: 9.079

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Journal:  J Foot Surg       Date:  1987 Jan-Feb

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Authors:  H G Dahmen
Journal:  Gesundheitswesen       Date:  1997-10

Review 5.  Effect of antimicrobial agents on the ecological balance of human microflora.

Authors:  A Sullivan; C Edlund; C E Nord
Journal:  Lancet Infect Dis       Date:  2001-09       Impact factor: 25.071

6.  High bacterial load in asymptomatic diabetic patients with neurotrophic ulcers retards wound healing after application of Dermagraft.

Authors:  A C Browne; M Vearncombe; R G Sibbald
Journal:  Ostomy Wound Manage       Date:  2001-10       Impact factor: 2.629

Review 7.  Preventing foot ulcers in patients with diabetes.

Authors:  Nalini Singh; David G Armstrong; Benjamin A Lipsky
Journal:  JAMA       Date:  2005-01-12       Impact factor: 56.272

8.  Foot infections in diabetes are rarely due to a single microorganism.

Authors:  J A Hunt
Journal:  Diabet Med       Date:  1992-10       Impact factor: 4.359

9.  Hospital admissions of diabetic patients: information from hospital activity analysis.

Authors:  D R Williams
Journal:  Diabet Med       Date:  1985-01       Impact factor: 4.359

10.  The efficacy of chemical agents in cleaning and disinfection programs.

Authors:  T C Penna; P G Mazzola; A M Silva Martins
Journal:  BMC Infect Dis       Date:  2001-09-24       Impact factor: 3.090

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