Literature DB >> 17035726

Thymidylate synthase as a chemotherapeutic drug target: where are we after fifty years?

Franklin G Berger1, Sondra H Berger.   

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Year:  2006        PMID： 17035726     DOI： 10.4161/cbt.5.9.3414

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN： 1538-4047            Impact factor:   4.742


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  11 in total

1.  Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer.

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Journal:  Pathol Oncol Res       Date:  2013-10-14       Impact factor: 3.201

2.  Cooperation between an intrinsically disordered region and a helical segment is required for ubiquitin-independent degradation by the proteasome.

Authors:  Sandra P Melo; Karen W Barbour; Franklin G Berger
Journal:  J Biol Chem       Date:  2011-08-30       Impact factor: 5.157

Review 3.  Participation of DNA repair in the response to 5-fluorouracil.

Authors:  M D Wyatt; D M Wilson
Journal:  Cell Mol Life Sci       Date:  2009-03       Impact factor: 9.261

4.  Oxidative Stress and Response to Thymidylate Synthase-Targeted Antimetabolites.

Authors:  Ufuk Ozer; Karen W Barbour; Sarah A Clinton; Franklin G Berger
Journal:  Mol Pharmacol       Date:  2015-10-06       Impact factor: 4.436

5.  The intrinsically disordered N-terminal domain of thymidylate synthase targets the enzyme to the ubiquitin-independent proteasomal degradation pathway.

Authors:  Maria Marjorette O Peña; Sandra P Melo; Yang-Yang Xing; Kenneth White; Karen W Barbour; Franklin G Berger
Journal:  J Biol Chem       Date:  2009-09-21       Impact factor: 5.157

6.  Transcriptome analysis reveals potential mechanisms underlying differential heart development in fast- and slow-growing broilers under heat stress.

Authors:  Jibin Zhang; Carl J Schmidt; Susan J Lamont
Journal:  BMC Genomics       Date:  2017-04-13       Impact factor: 3.969

7.  Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.

Authors:  Kinga Nyíri; Haydyn D T Mertens; Borbála Tihanyi; Gergely N Nagy; Bianka Kőhegyi; Judit Matejka; Matthew J Harris; Judit E Szabó; Veronika Papp-Kádár; Veronika Németh-Pongrácz; Olivér Ozohanics; Károly Vékey; Dmitri I Svergun; Antoni J Borysik; Beáta G Vértessy
Journal:  Sci Rep       Date:  2018-03-12       Impact factor: 4.379

8.  5-Fluorouracil treatment induces characteristic T>G mutations in human cancer.

Authors:  Sharon Christensen; Bastiaan Van der Roest; Nicolle Besselink; Roel Janssen; Sander Boymans; John W M Martens; Marie-Laure Yaspo; Peter Priestley; Ewart Kuijk; Edwin Cuppen; Arne Van Hoeck
Journal:  Nat Commun       Date:  2019-10-08       Impact factor: 14.919

9.  Characterization of the bipartite degron that regulates ubiquitin-independent degradation of thymidylate synthase.

Authors:  Karen W Barbour; Yang-Yang Xing; Edsel A Peña; Franklin G Berger
Journal:  Biosci Rep       Date:  2013-01-18       Impact factor: 3.840

10.  An FDA-Drug Library Screen for Compounds with Bioactivities against Meticillin-Resistant Staphylococcus aureus (MRSA).

Authors:  Qiu Ying Lau; Yoke Yan Fion Tan; Vanessa Chai Yin Goh; David Jing Qin Lee; Fui Mee Ng; Esther H Q Ong; Jeffrey Hill; Cheng San Brian Chia
Journal:  Antibiotics (Basel)       Date:  2015-10-09
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