Literature DB >> 17033636

The genetics of autistic disorders and its clinical relevance: a review of the literature.

C M Freitag1.   

Abstract

Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially delineate the phenotype of AD and discuss aspects of differential diagnosis, which are particularly relevant with regard to the genetics of autism. Cytogenetic and molecular genetic studies will be presented in detail, and the possibly involved aetiopathological pathways will be described. Implications of the different genetic findings for genetic counselling will be mentioned.

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Mesh：

Year:  2006        PMID： 17033636     DOI： 10.1038/sj.mp.4001896

Source DB:  PubMed          Journal:  Mol Psychiatry        ISSN： 1359-4184            Impact factor:   15.992


  207 in total

1.  Genome-wide association scan of korean autism spectrum disorders with language delay: a preliminary study.

Authors:  Soo-Churl Cho; Hee Jeong Yoo; Mira Park; In Hee Cho; Boong-Nyun Kim; Jae-Won Kim; Min-Sup Shin; Tae-Won Park; Jung-Woo Son; Un-Sun Chung; Hyo-Won Kim; Young-Hui Yang; Je-Ouk Kang; So Young Yang; Soon Ae Kim
Journal:  Psychiatry Investig       Date:  2011-02-25       Impact factor: 2.505

2.  Genome-scan for IQ discrepancy in autism: evidence for loci on chromosomes 10 and 16.

Authors:  Nicola H Chapman; Annette Estes; Jeff Munson; Raphael Bernier; Sara J Webb; Joseph H Rothstein; Nancy J Minshew; Geraldine Dawson; Gerard D Schellenberg; Ellen M Wijsman
Journal:  Hum Genet       Date:  2010-10-21       Impact factor: 4.132

3.  Risk factors of autistic symptoms in children with ADHD.

Authors:  Anne Kröger; Susann Hänig; Christiane Seitz; Haukur Palmason; Jobst Meyer; Christine M Freitag
Journal:  Eur Child Adolesc Psychiatry       Date:  2011-10-16       Impact factor: 4.785

4.  Variants in several genomic regions associated with asperger disorder.

Authors:  D Salyakina; D Q Ma; J M Jaworski; I Konidari; P L Whitehead; R Henson; D Martinez; J L Robinson; S Sacharow; H H Wright; R K Abramson; J R Gilbert; M L Cuccaro; M A Pericak-Vance
Journal:  Autism Res       Date:  2010-12       Impact factor: 5.216

5.  No evidence for significant association between GABA receptor genes in chromosome 15q11-q13 and autism in a Japanese population.

Authors:  Mamoru Tochigi; Chieko Kato; Shinko Koishi; Yuki Kawakubo; Kenji Yamamoto; Hideo Matsumoto; Ohiko Hashimoto; Soo-Yung Kim; Keiichiro Watanabe; Yukiko Kano; Eiji Nanba; Nobumasa Kato; Tsukasa Sasaki
Journal:  J Hum Genet       Date:  2007-10-24       Impact factor: 3.172

6.  Support for the involvement of large copy number variants in the pathogenesis of schizophrenia.

Authors:  George Kirov; Detelina Grozeva; Nadine Norton; Dobril Ivanov; Kiran K Mantripragada; Peter Holmans; Nick Craddock; Michael J Owen; Michael C O'Donovan
Journal:  Hum Mol Genet       Date:  2009-01-29       Impact factor: 6.150

Review 7.  Using genetic findings in autism for the development of new pharmaceutical compounds.

Authors:  Jacob A S Vorstman; Will Spooren; Antonio M Persico; David A Collier; Stefan Aigner; Ravi Jagasia; Jeffrey C Glennon; Jan K Buitelaar
Journal:  Psychopharmacology (Berl)       Date:  2013-11-30       Impact factor: 4.530

8.  Combined effect of maternal serotonin transporter genotype and prenatal stress in modulating offspring social interaction in mice.

Authors:  Karen L Jones; Ryan M Smith; Kristin S Edwards; Bennet Givens; Michael R Tilley; David Q Beversdorf
Journal:  Int J Dev Neurosci       Date:  2010-05-12       Impact factor: 2.457

9.  Variants in TTC25 affect autistic trait in patients with autism spectrum disorder and general population.

Authors:  Dina Vojinovic; Nathalie Brison; Shahzad Ahmad; Ilse Noens; Irene Pappa; Lennart C Karssen; Henning Tiemeier; Cornelia M van Duijn; Hilde Peeters; Najaf Amin
Journal:  Eur J Hum Genet       Date:  2017-05-17       Impact factor: 4.246

10.  Heterogeneous dysregulation of microRNAs across the autism spectrum.

Authors:  Kawther Abu-Elneel; Tsunglin Liu; Francesca S Gazzaniga; Yuhei Nishimura; Dennis P Wall; Daniel H Geschwind; Kaiqin Lao; Kenneth S Kosik
Journal:  Neurogenetics       Date:  2008-06-19       Impact factor: 2.660
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