Literature DB >> 17030716

Effect of medical therapy on glaucoma filtration surgery rates in Ontario.

Rony Rachmiel1, Graham E Trope, Mary L Chipman, Pieter Gouws, Yvonne M Buys.   

Abstract

OBJECTIVE: To analyze trends of glaucoma filtration surgery in Ontario.
METHODS: From April 1, 1992, through March 31, 2004, correlations were examined between the annual rates of trabeculectomies in Ontario, the use of glaucoma medications, and the numbers of practicing ophthalmologists and optometrists.
RESULTS: The number of trabeculectomies per 1000 persons at risk for primary open-angle glaucoma increased from 33.5 in 1992 to 46.2 in 1996 (37.7% increase; 6.6% increase per year) and then steadily decreased to 38.2 in 2004 (17.0% decrease; 2.7% decrease per year). The number of glaucoma medications dispensed in Ontario increased from 766 000 in 1992 to 1 466 543 in 2004 (91.5% increase; 10.5% annual increase). The increase in dispensed prostaglandin analogues strongly correlated (P<.001; 95% confidence interval, -0.87 to -0.41) with the decreasing number of trabeculectomies. The decreasing number of ophthalmologists positively correlated (r = 0.87) with the filtration surgery rate after 1997.
CONCLUSIONS: The number of trabeculectomies has decreased substantially in Ontario coinciding with the introduction of medications for the treatment of glaucoma in December 1996. This decrease in trabeculectomies highly correlated with the introduction of prostaglandin analogues (P<.001) and the decreasing number of ophthalmologists from 1997 through 2004.

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Year:  2006        PMID: 17030716     DOI: 10.1001/archopht.124.10.1472

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  6 in total

Review 1.  Discovery, characterization and clinical utility of prostaglandin agonists for the treatment of glaucoma.

Authors:  Peter G Klimko; Najam A Sharif
Journal:  Br J Pharmacol       Date:  2018-05-17       Impact factor: 8.739

2.  Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery.

Authors:  Nanako Awai-Kasaoka; Toshihiro Inoue; Masaru Inatani; Yuji Takihara; Minako Ogata-Iwao; Hidenobu Tanihara
Journal:  Jpn J Ophthalmol       Date:  2013-08-03       Impact factor: 2.447

3.  Global rates of glaucoma surgery.

Authors:  Kaweh Mansouri; Felipe A Medeiros; Robert N Weinreb
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-09-26       Impact factor: 3.117

4.  A new manner of reporting pressure results after glaucoma surgery.

Authors:  Constantin-Dan Bordeianu; Cristina-Eugenia Ticu
Journal:  Clin Ophthalmol       Date:  2011-12-30

5.  Editorial New Advances in Diagnosis and Management of Glaucoma.

Authors:  M Reza Razeghinejad; Mohammad H Nowroozzadeh
Journal:  Open Ophthalmol J       Date:  2015-05-15

Review 6.  Different strategies and cost-effectiveness in the treatment of primary open angle glaucoma.

Authors:  Naomi Sj Ting; James Ft Li Yim; Jia Y Ng
Journal:  Clinicoecon Outcomes Res       Date:  2014-12-04
  6 in total

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