| Literature DB >> 17030585 |
J Scott Ferguson1, Jennifer L Martin, Abul K Azad, Travis R McCarthy, Peter B Kang, Dennis R Voelker, Erika C Crouch, Larry S Schlesinger.
Abstract
Lung surfactant protein D (SP-D) binds to Mycobacterium tuberculosis surface lipoarabinomannan and results in bacterial agglutination, reduced uptake, and inhibition of growth in human macrophages. Here we show that SP-D limits the intracellular growth of bacilli in macrophages by increasing phagosome-lysosome fusion but not by generating a respiratory burst.Entities:
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Year: 2006 PMID: 17030585 PMCID: PMC1698096 DOI: 10.1128/IAI.01402-06
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441