Literature DB >> 17028529

[Nosocomial influenza outbreak in a geriatrics department: Effectiveness of preventive measures].

Anne-Gaëlle Andrieu1, Jocelyne Paute, Laure Glomot, Vincent Jarlier, Joël Belmin.   

Abstract

OBJECTIVE: To describe a nosocomial influenza outbreak and the pharmacologic and nonpharmacologic control measures implemented in a hospital ward with beds for acute geriatric care and rehabilitation care.
METHODS: Descriptive survey conducted in the geriatrics department of a university hospital. An influenza outbreak occurred in February 2005 in 2 of the department's 3 separate units. The study concerned all patients in the 2 affected units (A and B) present during the outbreak, as well as all department staff. Once cases of influenza were confirmed, elderly patients in contact with influenza patients received chemoprophylaxis with oseltamivir when it became available.
RESULTS: Thirty-eight (76%) patients and 62 (38%) staff members had been vaccinated. The time from the initial symptoms of the first case until implementation of control measures was 7 days in unit A but only 1 day in unit B, -and chemoprophylaxis of contact patients began in 9 days and 24 hours respectively. The attack rate was 38% in the 38 vaccinated patients and 29% in the 14 unvaccinated patients (NS). All cases met the definition of nosocomial infection. No deaths imputable to influenza occurred during the outbreak. The implementation of the nonpharmacologic measures aimed at preventing spread of the outbreak presented no particular difficulty, except for compliance with geographic isolation of some patients with dementia and influenza. The difference between the attack rates for the two sectors (48% for unit A and 28% for unit B) suggests that the preventive measures were effective. Tolerance to chemoprophylaxis with oseltamivir was good.
CONCLUSION: This study confirmed that influenza can affect elderly hospital patients, even those in whom the vaccination rate is high, and that rapid detection of the outbreak and immediate implementation of pharmacologic and nonpharmacologic preventive measures can limit its spread.

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Year:  2006        PMID: 17028529     DOI: 10.1016/s0755-4982(06)74830-8

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  4 in total

1.  Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.

Authors:  Timothy M Uyeki; Henry H Bernstein; John S Bradley; Janet A Englund; Thomas M File; Alicia M Fry; Stefan Gravenstein; Frederick G Hayden; Scott A Harper; Jon Mark Hirshon; Michael G Ison; B Lynn Johnston; Shandra L Knight; Allison McGeer; Laura E Riley; Cameron R Wolfe; Paul E Alexander; Andrew T Pavia
Journal:  Clin Infect Dis       Date:  2019-03-05       Impact factor: 9.079

2.  Five years of hospital based surveillance of influenza-like illness and influenza in a short-stay geriatric unit.

Authors:  Corinne Régis; Nicolas Voirin; Vanessa Escuret; Byeul-A Kim; Olivier Robert; Bruno Lina; Brigitte Comte; Philippe Vanhems
Journal:  BMC Res Notes       Date:  2014-02-21

3.  Can epidemic detection systems at the hospital level complement regional surveillance networks: case study with the influenza epidemic?

Authors:  Solweig Gerbier-Colomban; Véronique Potinet-Pagliaroli; Marie-Hélène Metzger
Journal:  BMC Infect Dis       Date:  2014-07-10       Impact factor: 3.090

4.  Molecular characterization of a nosocomial outbreak of influenza B virus in an acute care hospital setting.

Authors:  M Sansone; Å Wiman; M L Karlberg; M Brytting; L Bohlin; L-M Andersson; J Westin; R Nordén
Journal:  J Hosp Infect       Date:  2018-08-23       Impact factor: 3.926

  4 in total

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