Literature DB >> 17026666

Keep the traffic moving: mechanism of the Hsp70 motor.

Rui Sousa1, Eileen M Lafer.   

Abstract

Hsp70s are ubiquitous chaperones that use ATP hydrolysis to drive a variety of protein processing reactions, including a number of steps in protein trafficking. Recent studies have shed light on how ATP might generate conformational changes in an Hsp70 molecule and how such changes might be harnessed to drive processes as diverse as protein import into subcellular organelles and uncoating of clathrin-coated vesicles.

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Year:  2006        PMID： 17026666      PMCID： PMC4445649          DOI： 10.1111/j.1600-0854.2006.00497.x

Source DB:  PubMed          Journal:  Traffic        ISSN： 1398-9219            Impact factor:   6.215


  55 in total

1.  Mutations in the substrate binding domain of the Escherichia coli 70 kDa molecular chaperone, DnaK, which alter substrate affinity or interdomain coupling.

Authors:  D L Montgomery; R I Morimoto; L M Gierasch
Journal:  J Mol Biol       Date:  1999-02-26       Impact factor: 5.469

2.  Kinetic analysis of interdomain coupling in a lidless variant of the molecular chaperone DnaK: DnaK's lid inhibits transition to the low affinity state.

Authors:  Sergey V Slepenkov; Stephan N Witt
Journal:  Biochemistry       Date:  2002-10-08       Impact factor: 3.162

Review 3.  Mitochondrial import and the twin-pore translocase.

Authors:  Peter Rehling; Katrin Brandner; Nikolaus Pfanner
Journal:  Nat Rev Mol Cell Biol       Date:  2004-07       Impact factor: 94.444

4.  Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae.

Authors:  B Miao; J E Davis; E A Craig
Journal:  J Mol Biol       Date:  1997-02-07       Impact factor: 5.469

5.  Structural basis of interdomain communication in the Hsc70 chaperone.

Authors:  Jianwen Jiang; Kondury Prasad; Eileen M Lafer; Rui Sousa
Journal:  Mol Cell       Date:  2005-11-23       Impact factor: 17.970

6.  Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.

Authors:  D Hanein; K E Matlack; B Jungnickel; K Plath; K U Kalies; K R Miller; T A Rapoport; C W Akey
Journal:  Cell       Date:  1996-11-15       Impact factor: 41.582

7.  Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK.

Authors:  C J Harrison; M Hayer-Hartl; M Di Liberto; F Hartl; J Kuriyan
Journal:  Science       Date:  1997-04-18       Impact factor: 47.728

8.  Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating.

Authors:  Alexander Fotin; Yifan Cheng; Nikolaus Grigorieff; Thomas Walz; Stephen C Harrison; Tomas Kirchhausen
Journal:  Nature       Date:  2004-10-24       Impact factor: 49.962

9.  J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix.

Authors:  Patrick D D'Silva; Brenda Schilke; William Walter; Amy Andrew; Elizabeth A Craig
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-06       Impact factor: 11.205

10.  Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ-1.

Authors:  B C Freeman; M P Myers; R Schumacher; R I Morimoto
Journal:  EMBO J       Date:  1995-05-15       Impact factor: 11.598
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  20 in total

1.  Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly.

Authors:  Yue Zhuo; Udayar Ilangovan; Virgil Schirf; Borries Demeler; Rui Sousa; Andrew P Hinck; Eileen M Lafer
Journal:  J Mol Biol       Date:  2010-09-25       Impact factor: 5.469

2.  Structural basis of J cochaperone binding and regulation of Hsp70.

Authors:  Jianwen Jiang; E Guy Maes; Alexander B Taylor; Liping Wang; Andrew P Hinck; Eileen M Lafer; Rui Sousa
Journal:  Mol Cell       Date:  2007-11-09       Impact factor: 17.970

Review 3.  The activities and function of molecular chaperones in the endoplasmic reticulum.

Authors:  Teresa M Buck; Christine M Wright; Jeffrey L Brodsky
Journal:  Semin Cell Dev Biol       Date:  2007-09-08       Impact factor: 7.727

4.  Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic.

Authors:  Branch Craige; Gloria Salazar; Victor Faundez
Journal:  Mol Biol Cell       Date:  2008-02-06       Impact factor: 4.138

5.  Structure of the Hsp110:Hsc70 nucleotide exchange machine.

Authors:  Jonathan P Schuermann; Jianwen Jiang; Jorge Cuellar; Oscar Llorca; Liping Wang; Luis E Gimenez; Suping Jin; Alexander B Taylor; Borries Demeler; Kevin A Morano; P John Hart; Jose M Valpuesta; Eileen M Lafer; Rui Sousa
Journal:  Mol Cell       Date:  2008-06-12       Impact factor: 17.970

6.  Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis.

Authors:  Andrija Finka; Pierre Goloubinoff
Journal:  Cell Stress Chaperones       Date:  2013-02-21       Impact factor: 3.667

7.  Sequence-dependent internalization of aggregating peptides.

Authors:  José R Couceiro; Rodrigo Gallardo; Frederik De Smet; Greet De Baets; Pieter Baatsen; Wim Annaert; Kenny Roose; Xavier Saelens; Joost Schymkowitz; Frederic Rousseau
Journal:  J Biol Chem       Date:  2014-11-12       Impact factor: 5.157

8.  Heat shock proteins in long-lived worms and mice with insulin/insulin-like signaling mutations.

Authors:  William R Swindell
Journal:  Aging (Albany NY)       Date:  2009-06-15       Impact factor: 5.682

9.  Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector.

Authors:  Li Xu; Xihui Shen; Andrew Bryan; Simran Banga; Michele S Swanson; Zhao-Qing Luo
Journal:  PLoS Pathog       Date:  2010-03-19       Impact factor: 6.823

10.  Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivo.

Authors:  Jennifer Hirst; Daniela A Sahlender; Sam Li; Nienke B Lubben; Georg H H Borner; Margaret S Robinson
Journal:  Traffic       Date:  2008-05-17       Impact factor: 6.215
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