Literature DB >> 1702627

Non-selective cation channels in basolateral-membrane vesicles from pars recta of rabbit kidney proximal tubule.

J Blokkebak-Poulsen1, M I Sheikh, C Jacobsen.   

Abstract

The characteristics of 86Rb+ fluxes through conductive channels in basolateral-membrane vesicles isolated from pars recta of rabbit kidney proximal tubule were investigated. In RbCl-, KCl- and NaCl-loaded vesicles a transient and almost equal accumulation of 86Rb+ was observed. The uptakes of 86Rb+ were inhibited to the same extent by 10 mM-BaCl2 in all loadings. The accumulation was driven by an electrical diffusion potential. The 86Rb+ flux was dependent on intravesicular Ca2+. Increasing concentrations of Ca2+ gradually decreased the 86Rb+ uptake. At 10 microM-Ca2+ the radioisotope flux was below 20% of control. The vesicles containing the channel showed very low selectivity among the univalent cations K+, Rb+, Li+, Na+ and choline+.

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Year:  1990        PMID： 1702627      PMCID： PMC1149785          DOI： 10.1042/bj2720839

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  18 in total

1.  Potassium channels in basolateral membrane vesicles from pars convoluta of rabbit proximal tubule.

Authors:  C Jacobsen; J Blokkebak-Poulsen; M I Sheikh
Journal:  FEBS Lett       Date:  1990-09-03       Impact factor: 4.124

2.  Ca2+ and pH regulation of K+ channels in membrane vesicles of rabbit proximal tubule.

Authors:  C Jacobsen; S Mollerup; M I Sheikh
Journal:  Am J Physiol       Date:  1990-06

3.  Ba2+-sensitive K+ channels in luminal-membrane vesicles from pars convoluta of rabbit proximal tubule.

Authors:  C Jacobsen; H Røigaard-Petersen; M I Sheikh
Journal:  FEBS Lett       Date:  1989-01-30       Impact factor: 4.124

4.  A Ca2-activated cation-selective channel in the basolateral membrane of the cortical thick ascending limb of Henle's loop of the mouse.

Authors:  J Teulon; M Paulais; M Bouthier
Journal:  Biochim Biophys Acta       Date:  1987-11-27

5.  Properties of single K+ channels in the basolateral membrane of rabbit proximal straight tubules.

Authors:  H Gögelein; R Greger
Journal:  Pflugers Arch       Date:  1987-10       Impact factor: 3.657

6.  Basolateral potassium channels in renal proximal tubule.

Authors:  H Sackin; L G Palmer
Journal:  Am J Physiol       Date:  1987-09

7.  A high affinity calcium-stimulated magnesium-dependent adenosine triphosphatase in rat adipocyte plasma membranes.

Authors:  H A Pershadsingh; J M McDonald
Journal:  J Biol Chem       Date:  1980-05-10       Impact factor: 5.157

8.  Sodium gradient-dependent L-glutamate transport in renal brush border membrane vesicles. Effect of an intravesicular > extravesicular potassium gradient.

Authors:  E G Schneider; B Sacktor
Journal:  J Biol Chem       Date:  1980-08-25       Impact factor: 5.157

9.  A simplification of the protein assay method of Lowry et al. which is more generally applicable.

Authors:  G L Peterson
Journal:  Anal Biochem       Date:  1977-12       Impact factor: 3.365

10.  An efficient method for the isolation and separation of basolateral-membrane and luminal-membrane vesicles from rabbit kidney cortex.

Authors:  M I Sheikh; U Kragh-Hansen; K E Jørgensen; H Røigaard-Petersen
Journal:  Biochem J       Date:  1982-11-15       Impact factor: 3.857
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  1 in total

Review 1.  Regulation of tubular transport via ion channels.

Authors:  R Greger; E Schlatter; M Bleich; J Hirsch
Journal:  Clin Investig       Date:  1993-10
  1 in total

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