| Literature DB >> 1702603 |
D R Colman1, S M Staugaitis, D D'Urso, M P Sinoway, B Allinquant, L Bernier, A Mentaberry, J G Stempak, P J Brophy.
Abstract
The transfection paradigm described herein can be used to investigate the functional properties of individual nervous system proteins in ways that have not been explored before. In particular, observations on the "structural" proteins of myelin are being made that have already yielded certain unique insights into the physiologic properties of these polypeptides. The ease with which site-directed mutagenesis procedures can be applied to these systems should eventually enable us to define with great precision the "functional domains" within each myelin protein.Mesh:
Substances:
Year: 1990 PMID: 1702603 DOI: 10.1111/j.1749-6632.1990.tb42403.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691