Literature DB >> 17025264

Issues related to targeted delivery of proteins and peptides.

Yingjuan Lu1, Jun Yang, Emanuela Sega.   

Abstract

While modern genomic and proteomic technology enables rapid screening of novel proteins and peptides as potential drug candidates, design of delivery systems for these biologics remains challenging especially to achieve site-specific pharmacological actions. This article discusses the issues associated with targeted delivery of protein and peptide drugs at physiochemical, physiological, and intracellular levels with a special focus on cancer therapy.

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Year:  2006        PMID： 17025264      PMCID： PMC2761053          DOI： 10.1208/aapsj080355

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


  110 in total

Review 1.  Peptides as carrier for tumor diagnosis and treatment.

Authors:  M Langer; A G Beck-Sickinger
Journal:  Curr Med Chem Anticancer Agents       Date:  2001-05

2.  Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins.

Authors:  Enrico Mastrobattista; Gerben A Koning; Louis van Bloois; Ana C S Filipe; Wim Jiskoot; Gert Storm
Journal:  J Biol Chem       Date:  2002-05-20       Impact factor: 5.157

3.  An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma.

Authors:  Stephen D Gillies; Yan Lan; Steven Williams; Frank Carr; Stephen Forman; Andrew Raubitschek; Kin-Ming Lo
Journal:  Blood       Date:  2005-02-03       Impact factor: 22.113

4.  Development of potent monoclonal antibody auristatin conjugates for cancer therapy.

Authors:  Svetlana O Doronina; Brian E Toki; Michael Y Torgov; Brian A Mendelsohn; Charles G Cerveny; Dana F Chace; Ron L DeBlanc; R Patrick Gearing; Tim D Bovee; Clay B Siegall; Joseph A Francisco; Alan F Wahl; Damon L Meyer; Peter D Senter
Journal:  Nat Biotechnol       Date:  2003-06-01       Impact factor: 54.908

5.  Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.

Authors:  Herbert Hurwitz; Louis Fehrenbacher; William Novotny; Thomas Cartwright; John Hainsworth; William Heim; Jordan Berlin; Ari Baron; Susan Griffing; Eric Holmgren; Napoleone Ferrara; Gwen Fyfe; Beth Rogers; Robert Ross; Fairooz Kabbinavar
Journal:  N Engl J Med       Date:  2004-06-03       Impact factor: 91.245

6.  Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity.

Authors:  Flavio Curnis; Anna Gasparri; Angelina Sacchi; Renato Longhi; Angelo Corti
Journal:  Cancer Res       Date:  2004-01-15       Impact factor: 12.701

Review 7.  Radiolabelled peptides for tumour therapy: current status and future directions. Plenary lecture at the EANM 2002.

Authors:  Marion de Jong; Dik Kwekkeboom; Roelf Valkema; Eric P Krenning
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-02-05       Impact factor: 9.236

Review 8.  Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas.

Authors:  Michael Weaver; Douglas W Laske
Journal:  J Neurooncol       Date:  2003-10       Impact factor: 4.130

9.  Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain.

Authors:  C P Leamon; I Pastan; P S Low
Journal:  J Biol Chem       Date:  1993-11-25       Impact factor: 5.486

10.  LEAPT: lectin-directed enzyme-activated prodrug therapy.

Authors:  Mark A Robinson; Stuart T Charlton; Philippe Garnier; Xiang-tao Wang; Stanley S Davis; Alan C Perkins; Malcolm Frier; Ruth Duncan; Tony J Savage; David A Wyatt; Susan A Watson; Benjamin G Davis
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-24       Impact factor: 11.205
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  23 in total

Review 1.  Improved Protein Toxin Delivery Based on ATTEMPTS Systems.

Authors:  Yingzhi Chen; Meng Zhang; Kyoung Ah Min; Huiyuan Wang; Meong Cheol Shin; Feng Li; Victor C Yang; Yongzhuo Huang
Journal:  Curr Drug Targets       Date:  2018-02-19       Impact factor: 3.465

Review 2.  Combinatorial peptide libraries: mining for cell-binding peptides.

Authors:  Bethany Powell Gray; Kathlynn C Brown
Journal:  Chem Rev       Date:  2013-12-03       Impact factor: 60.622

3.  Improved mucoadhesion and cell uptake of chitosan and chitosan oligosaccharide surface-modified polymer nanoparticles for mucosal delivery of proteins.

Authors:  Sathish Dyawanapelly; Uday Koli; Vimisha Dharamdasani; Ratnesh Jain; Prajakta Dandekar
Journal:  Drug Deliv Transl Res       Date:  2016-08       Impact factor: 4.617

4.  Improving matrix metalloproteinase-2 specific response of a hydrogel system using electrophoresis.

Authors:  Yu Zhang; Richard A Gemeinhart
Journal:  Int J Pharm       Date:  2012-03-13       Impact factor: 5.875

5.  Thiol-ene click hydrogels for therapeutic delivery.

Authors:  Prathamesh M Kharkar; Matthew S Rehmann; Kelsi M Skeens; Emanual Maverakis; April M Kloxin
Journal:  ACS Biomater Sci Eng       Date:  2016-01-11

6.  Ultrashort echo time (UTE) imaging of receptor targeted magnetic iron oxide nanoparticles in mouse tumor models.

Authors:  Liya Wang; Xiaodong Zhong; Weiping Qian; Jing Huang; Zehong Cao; Qiqi Yu; Malgorzata Lipowska; Run Lin; Andrew Wang; Lily Yang; Hui Mao
Journal:  J Magn Reson Imaging       Date:  2014-11       Impact factor: 4.813

7.  Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60.

Authors:  Sumit Majumdar; Bimo A Tejo; Ahmed H Badawi; David Moore; Jeffrey P Krise; Teruna J Siahaan
Journal:  Mol Pharm       Date:  2009 Mar-Apr       Impact factor: 4.939

8.  Freeze drying of peptide drugs self-associated with long-circulating, biocompatible and biodegradable sterically stabilized phospholipid nanomicelles.

Authors:  Sok Bee Lim; Israel Rubinstein; Hayat Onyüksel
Journal:  Int J Pharm       Date:  2008-01-17       Impact factor: 5.875

9.  The D-form of a novel heparan binding peptide decreases cytomegalovirus infection in vivo and in vitro.

Authors:  Elisabeth A Pitt; Pranay Dogra; Ravi S Patel; Angela Williams; Jonathan S Wall; Tim E Sparer
Journal:  Antiviral Res       Date:  2016-09-25       Impact factor: 5.970

10.  Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel.

Authors:  Pål K Selbo; Michael G Rosenblum; Lawrence H Cheung; Wendy Zhang; Kristian Berg
Journal:  PLoS One       Date:  2009-08-19       Impact factor: 3.240
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