| Literature DB >> 17025019 |
Jae-Hyuk Jang1, Kaneo Kanoh, Kyoko Adachi, Yoshikazu Shizuri.
Abstract
Awajanoran (1), a new dihydrobenzofuran derivative, was isolated from an agar-culture of Acremonium sp. AWA16-1, which had been isolated from sea mud collected at Awajishima Island in Japan. The structure of 1 was elucidated on the basis of a spectroscopic analysis. This compound inhibited the growth of A549 cells, the human lung adenocarcinoma cell line, with an IC50 value of 17 microg/ml, and also showed antimicrobial activity.Entities:
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Year: 2006 PMID： 17025019 DOI： 10.1038/ja.2006.60
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649