| Literature DB >> 17024846 |
Xiang Lan Piao1, Hye Hyun Yoo, Hyun Young Kim, Tak Lim Kang, Gwi Seo Hwang, Jeong Hill Park.
Abstract
In our efforts to discover novel phytoestrogens to treat menopausal symptoms, eleven furanocoumarins were isolated from Angelica dahurica and tested for their estrogenic activity on the Ishikawa cell line. Among the compounds tested, 9-hydroxy-4-methoxypsoralen and alloisoimperatorin showed strong abilities to induce alkaline phosphatase (AP) with EC50 values of 1.1 and 0.8 microg/mL, respectively, whereas the other nine furanocoumarins were weakly or only slightly active.Entities:
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Year: 2006 PMID： 17024846 DOI： 10.1007/BF02974073
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946