Literature DB >> 17024162

Regulation of ENaCs by proteases: An increasingly complex story.

T R Kleyman1, M M Myerburg, R P Hughey.   

Abstract

Proteolytic processing of epithelial Na+ channel (ENaC) subunits has an important role in the regulation of ENaC gating. This Commentary addresses the potential roles of specific proteases and protease inhibitors in the control of Na+ channel gating.

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Substances:

Year:  2006        PMID: 17024162     DOI: 10.1038/sj.ki.5001860

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  23 in total

1.  Firewall function of the endothelial glycocalyx in the regulation of sodium homeostasis.

Authors:  Stefanie Korte; Anne Wiesinger; Alexandra S Straeter; Wladimir Peters; Hans Oberleithner; Kristina Kusche-Vihrog
Journal:  Pflugers Arch       Date:  2011-11-05       Impact factor: 3.657

Review 2.  Regulation of the epithelial sodium channel (ENaC) by membrane trafficking.

Authors:  Michael B Butterworth
Journal:  Biochim Biophys Acta       Date:  2010-03-27

Review 3.  Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).

Authors:  P H Thibodeau; M B Butterworth
Journal:  Cell Tissue Res       Date:  2012-05-22       Impact factor: 5.249

4.  Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells.

Authors:  Ke Li; Dehuang Guo; Haidong Zhu; Kathleen S Hering-Smith; L Lee Hamm; Jingping Ouyang; Yanbin Dong
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2010-05-26       Impact factor: 3.619

Review 5.  ENaC structure and function in the wake of a resolved structure of a family member.

Authors:  Ossama B Kashlan; Thomas R Kleyman
Journal:  Am J Physiol Renal Physiol       Date:  2011-07-13

6.  Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.

Authors:  Alexei Diakov; Katarzyna Bera; Marianna Mokrushina; Bettina Krueger; Christoph Korbmacher
Journal:  J Physiol       Date:  2008-07-31       Impact factor: 5.182

7.  Deubiquitylation regulates activation and proteolytic cleavage of ENaC.

Authors:  Dorothée Ruffieux-Daidié; Olivier Poirot; Sheerazed Boulkroun; François Verrey; Stephan Kellenberger; Olivier Staub
Journal:  J Am Soc Nephrol       Date:  2008-08-13       Impact factor: 10.121

Review 8.  Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC).

Authors:  Johannes Loffing; Christoph Korbmacher
Journal:  Pflugers Arch       Date:  2009-03-11       Impact factor: 3.657

9.  Plasmin in nephrotic urine activates the epithelial sodium channel.

Authors:  Per Svenningsen; Claus Bistrup; Ulla G Friis; Marko Bertog; Silke Haerteis; Bettina Krueger; Jane Stubbe; Ole Nørregaard Jensen; Helle C Thiesson; Torben R Uhrenholt; Bente Jespersen; Boye L Jensen; Christoph Korbmacher; Ole Skøtt
Journal:  J Am Soc Nephrol       Date:  2008-12-10       Impact factor: 10.121

10.  Over- or underfill: not all nephrotic states are created equal.

Authors:  Detlef Bockenhauer
Journal:  Pediatr Nephrol       Date:  2013-03-26       Impact factor: 3.714

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