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Literature DB >> 17024113

t(3;12)(q26;q14) in polycythemia vera is associated with upregulation of the HMGA2 gene.

C T Storlazzi, F Albano, C Locunsolo, A Lonoce, S Funes, M C Guastadisegni, L Cimarosto, L Impera, P D'Addabbo, I Panagopoulos, G Specchia, M Rocchi.

Abstract

Entities: Disease Gene

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Year: 2006 PMID： 17024113 DOI： 10.1038/sj.leu.2404418

Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528

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12 in total

1. Increased likelihood of post-polycythemia vera myelofibrosis in Ph-negative MPN patients with chromosome 12 abnormalities.

Authors: Christopher B Benton; Maria Tanaka; Catherine Wilson; Sherry Pierce; Lingsha Zhou; Jorge Cortes; Hagop Kantarjian; Srdan Verstovsek
Journal: Leuk Res Date: 2015-02-02 Impact factor: 3.156

2. Stat3-positive tumor cells contribute to vessels neoformation in primary central nervous system lymphoma.

Authors: Simona Ruggieri; Roberto Tamma; Nicoletta Resta; Francesco Albano; Nicoletta Coccaro; Daria Loconte; Tiziana Annese; Mariella Errede; Giorgina Specchia; Rebecca Senetta; Paola Cassoni; Domenico Ribatti; Beatrice Nico
Journal: Oncotarget Date: 2017-05-09

3. HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma.

Authors: Alexandra C Hristov; Leslie Cope; Marcelo Delos Reyes; Mansher Singh; Christine Iacobuzio-Donahue; Anirban Maitra; L M S Resar
Journal: Mod Pathol Date: 2008-08-29 Impact factor: 7.842

4. Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.

Authors: Kentson Lam; Alexander Muselman; Randal Du; Yuka Harada; Amanda G Scholl; Ming Yan; Shinobu Matsuura; Stephanie Weng; Hironori Harada; Dong-Er Zhang
Journal: Blood Date: 2014-08-22 Impact factor: 22.113

5. TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing.

Authors: Crescenzio Francesco Minervini; Cosimo Cumbo; Paola Orsini; Claudia Brunetti; Luisa Anelli; Antonella Zagaria; Angela Minervini; Paola Casieri; Nicoletta Coccaro; Giuseppina Tota; Luciana Impera; Annamaria Giordano; Giorgina Specchia; Francesco Albano
Journal: Diagn Pathol Date: 2016-10-10 Impact factor: 2.644

6. Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia.

Authors: Angela Minervini; Crescenzio Francesco Minervini; Luisa Anelli; Antonella Zagaria; Paola Casieri; Nicoletta Coccaro; Cosimo Cumbo; Giuseppina Tota; Luciana Impera; Paola Orsini; Claudia Brunetti; Annamaria Giordano; Giorgina Specchia; Francesco Albano
Journal: Oncotarget Date: 2016-12-27

t(3;12)(q26;q14) in polycythemia vera is associated with upregulation of the HMGA2 gene.

1. Increased likelihood of post-polycythemia vera myelofibrosis in Ph-negative MPN patients with chromosome 12 abnormalities.

2. Stat3-positive tumor cells contribute to vessels neoformation in primary central nervous system lymphoma.

3. HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma.

4. Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.

5. TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing.

6. Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia.

7. Aberrant let7a/HMGA2 signaling activity with unique clinical phenotype in JAK2-mutated myeloproliferative neoplasms.

Review 8. Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies.

9. Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells.

Review 10. TP53 in Myelodysplastic Syndromes: Recent Biological and Clinical Findings.