Literature DB >> 1702395

Cloning and sequence analysis of a cDNA encoding a precursor for rat C-type natriuretic peptide (CNP).

M Kojima1, N Minamino, K Kangawa, H Matsuo.   

Abstract

Recent identification of a C-type natriuretic peptide (CNP) in porcine brain strongly suggested that a third member of the natriuretic peptide family still remains to be identified in other species of mammals. A cDNA encoding a precursor for rat CNP was cloned from a rat brain cDNA library and sequenced. The precursor was a 126-residue peptide, carrying a 23-residue signal sequence at the N-terminus and the known porcine CNP-53 sequence at the C-terminus. By RNA blot analysis, rat CNP mRNA was found to be expressed exclusively in the brain, implying that CNP may function in the central nervous system as a neuropeptide.

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Year:  1990        PMID： 1702395     DOI： 10.1016/0014-5793(90)80544-s

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  21 in total

1.  Three dimensional atomic model and experimental validation for the ATP-Regulated Module (ARM) of the atrial natriuretic factor receptor guanylate cyclase.

Authors:  T Duda; P Yadav; A Jankowska; V Venkataraman; R K Sharma
Journal:  Mol Cell Biochem       Date:  2001-01       Impact factor: 3.396

2.  Three dimensional atomic model and experimental validation for the ATP-Regulated Module (ARM) of the atrial natriuretic factor receptor guanylate cyclase.

Authors:  T Duda; P Yadav; A Jankowska; V Venkataraman; R K Sharma
Journal:  Mol Cell Biochem       Date:  2000-11       Impact factor: 3.396

3.  Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases.

Authors:  K J Koller; F J de Sauvage; D G Lowe; D V Goeddel
Journal:  Mol Cell Biol       Date:  1992-06       Impact factor: 4.272

4.  Differential regional expression of three natriuretic peptide receptor genes within primate tissues.

Authors:  J N Wilcox; A Augustine; D V Goeddel; D G Lowe
Journal:  Mol Cell Biol       Date:  1991-07       Impact factor: 4.272

5.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-08-25       Impact factor: 16.971

6.  Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide.

Authors:  N Murayama; M A Hayashi; H Ohi; L A Ferreira; V V Hermann; H Saito; Y Fujita; S Higuchi; B L Fernandes; T Yamane; A C de Camargo
Journal:  Proc Natl Acad Sci U S A       Date:  1997-02-18       Impact factor: 11.205

7.  Characterization of a C-type natriuretic peptide (CNP-39)-formed cation-selective channel from platypus (Ornithorhynchus anatinus) venom.

Authors:  J I Kourie
Journal:  J Physiol       Date:  1999-07-15       Impact factor: 5.182

8.  Differential regulation of natriuretic peptide receptors on ciliary body epithelial cells.

Authors:  R B Crook; A T Chang
Journal:  Biochem J       Date:  1997-05-15       Impact factor: 3.857

9.  Cell-type-specific function of the C-type natriuretic peptide gene promoter in rat anterior pituitary-derived cultured cell lines.

Authors:  S Ohta; Y Shimekake; K Nagata
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

10.  Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".

Authors:  S Suga; K Nakao; H Itoh; Y Komatsu; Y Ogawa; N Hama; H Imura
Journal:  J Clin Invest       Date:  1992-09       Impact factor: 14.808
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