Literature DB >> 17023255

An experimental pain model to investigate the specificity of the neurodynamic test for the median nerve in the differential diagnosis of hand symptoms.

Michel W Coppieters1, Ali M Alshami, Paul W Hodges.   

Abstract

OBJECTIVE: To indirectly assess the specificity of the neurodynamic test for the median nerve using an experimental pain model.
DESIGN: Repeated-measures design.
SETTING: Laboratory setting. PARTICIPANTS: Twenty asymptomatic participants in whom hand symptoms were induced by infusion of hypertonic saline into the thenar muscles.
INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Pain intensity of the induced hand symptoms and size of the painful area were evaluated in 8 different arm positions, which correspond with different stages of the neurodynamic test for the median nerve. These positions have a variable degree of median nerve provocation at the wrist.
RESULTS: Because the induced symptoms had a non-neural origin, changes in symptom provocation with the neurodynamic test would have indicated poor specificity. However, there were no statistically significant differences in pain perception (P> or =.22) and the recorded differences were negligible from a clinical perspective.
CONCLUSIONS: Taking into consideration the limitations of an experimental pain model, this study indirectly confirms the specificity of the neurodynamic test for the median nerve. The results of this study, together with previous studies that demonstrated a high sensitivity, support the use of the neurodynamic test for the median nerve to differentially diagnose neurogenic disorders, such as carpal tunnel syndrome, from other wrist and hand pathologies.

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Year:  2006        PMID: 17023255     DOI: 10.1016/j.apmr.2006.06.012

Source DB:  PubMed          Journal:  Arch Phys Med Rehabil        ISSN: 0003-9993            Impact factor:   3.966


  6 in total

1.  An investigation of somatosensory profiles in work related upper limb disorders: a case-control observational study protocol.

Authors:  Niamh Moloney; Toby Hall; Catherine Doody
Journal:  BMC Musculoskelet Disord       Date:  2010-01-30       Impact factor: 2.362

2.  Exogenously applied muscle metabolites synergistically evoke sensations of muscle fatigue and pain in human subjects.

Authors:  Kelly A Pollak; Jeffrey D Swenson; Timothy A Vanhaitsma; Ronald W Hughen; Daehyun Jo; Andrea T White; Kathleen C Light; Petra Schweinhardt; Markus Amann; Alan R Light
Journal:  Exp Physiol       Date:  2013-10-18       Impact factor: 2.969

3.  Upper Limb Neurodynamic Test 1 on Healthy Individuals: Intra- and Intersession Reliability of the Angle between Pain Onset and Submaximal Pain.

Authors:  Diego Leoni; Davide Storer; Roberto Gatti; Michele Egloff; Marco Barbero
Journal:  Pain Res Manag       Date:  2016-09-22       Impact factor: 3.037

Review 4.  Does the efficacy of neurodynamic treatments depend on the presence and type of criteria used to define neural mechanosensitivity in spinally-referred leg pain? A systematic review and meta-analysis.

Authors:  Tawanda Murape; Timothy R Ainslie; Cato A Basson; Annina B Schmid
Journal:  S Afr J Physiother       Date:  2022-07-22

5.  Reliability of clinical tests to evaluate nerve function and mechanosensitivity of the upper limb peripheral nervous system.

Authors:  Annina B Schmid; Florian Brunner; Hannu Luomajoki; Ulrike Held; Lucas M Bachmann; Sabine Künzer; Michel W Coppieters
Journal:  BMC Musculoskelet Disord       Date:  2009-01-21       Impact factor: 2.362

6.  New Insight into the Time-Course of Motor and Sensory System Changes in Pain.

Authors:  Siobhan M Schabrun; Emma Burns; Paul W Hodges
Journal:  PLoS One       Date:  2015-11-24       Impact factor: 3.240

  6 in total

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