Laura M Gaudet1, Jennifer MacKenzie2, Graeme N Smith1. 1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Kingston General Hospital, Queen's University, Kingston ON. 2. Department of Medical Genetics, Kingston General Hospital, Queen's University, Kingston ON.
Abstract
BACKGROUND: Abetalipoproteinemia (ABL) is a metabolic disorder resulting in poor absorption of fat-soluble vitamins. CASE: Two pregnancies in a woman with ABL are reported, contrasting outcomes with subtherapeutic and normal vitamin levels. CONCLUSION: Fat-soluble vitamin levels in pregnancy are critical for many aspects of fetal development. This report details a congenital ophthalmologic finding that may be associated with vitamin A deficiency.
BACKGROUND:Abetalipoproteinemia (ABL) is a metabolic disorder resulting in poor absorption of fat-soluble vitamins. CASE: Two pregnancies in a woman with ABL are reported, contrasting outcomes with subtherapeutic and normal vitamin levels. CONCLUSION: Fat-soluble vitamin levels in pregnancy are critical for many aspects of fetal development. This report details a congenital ophthalmologic finding that may be associated with vitamin A deficiency.
Authors: Evan B Selzer; Delphine Blain; Robert B Hufnagel; Philip J Lupo; Laura E Mitchell; Brian P Brooks Journal: Surv Ophthalmol Date: 2021-12-31 Impact factor: 6.197