| Literature DB >> 17021111 |
Shoko Okitsu-Negishi1, Michio Okame, Yuko Shimizu, Tung Gia Phan, Takeshi Tomaru, Shigenori Kamijo, Takashi Sato, Fumihiro Yagyu, Werner E G Müller, Hiroshi Ushijima.
Abstract
The commercial norovirus enzyme-linked immunosorbent assay kit was evaluated for its reactivity to recombinant virus-like particles and the detection of natural viruses from stool samples of Japanese infants and children with sporadic acute gastroenteritis compared to reverse transcription-PCR. The kit had a sensitivity of 76.3% and a specificity of 94.9%. Our results clearly indicated that the kit allows the detection of the most prevalent genotype, GII/4. In order to increase the sensitivity of the kit, the reactivity with norovirus of GII/3 and GII/6 genotypes needs to be improved.Entities:
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Year: 2006 PMID: 17021111 PMCID: PMC1594799 DOI: 10.1128/JCM.01373-06
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948