Literature DB >> 17021056

Combined hepatitis C virus (HCV) antigen-antibody detection assay does not improve diagnosis for seronegative individuals with occult HCV infection.

Juan A Quiroga1, Inmaculada Castillo, Margarita Pardo, Elena Rodríguez-Iñigo, Vicente Carreño.   

Abstract

A combined hepatitis C virus (HCV) antigen-antibody assay was evaluated for 115 seronegative individuals with occult HCV infection. The assay was reactive in one patient and negative to weakly reactive in three others (all four gave indeterminate results by supplemental assay) but failed to detect HCV in the remaining patients. Despite increased sensitivity the combined assay does not improve serodiagnosis of occult HCV infection.

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Year:  2006        PMID: 17021056      PMCID: PMC1698377          DOI: 10.1128/JCM.01440-06

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  11 in total

1.  T-cell responses and previous exposure to hepatitis C virus in indeterminate blood donors.

Authors:  Nasser Semmo; Eleanor Barnes; Craig Taylor; John Kurtz; Gillian Harcourt; Neil Smith; Paul Klenerman
Journal:  Lancet       Date:  2005 Jan 22-28       Impact factor: 79.321

2.  HCV-indeterminate blood donors or occult HCV infection?

Authors:  Juan A Quiroga; Vicente Carreño
Journal:  Lancet       Date:  2005 Apr 30-May 6       Impact factor: 79.321

3.  Is an assay for simultaneous detection of hepatitis C virus core antigen and antibody a valuable alternative to nucleic acid testing?

Authors:  Syria Laperche; Marie-Hélène Elghouzzi; Pascal Morel; Marianne Asso-Bonnet; Nadine Le Marrec; Annie Girault; Annabelle Servant-Delmas; Françoise Bouchardeau; Marie Deschaseaux; Yves Piquet
Journal:  Transfusion       Date:  2005-12       Impact factor: 3.157

4.  Combination hepatitis C virus antigen and antibody immunoassay as a new tool for early diagnosis of infection.

Authors:  F Ansaldi; B Bruzzone; G Testino; M Bassetti; R Gasparini; P Crovari; G Icardi
Journal:  J Viral Hepat       Date:  2006-01       Impact factor: 3.728

5.  Simultaneous detection of hepatitis C virus (HCV) core antigen and anti-HCV antibodies improves the early detection of HCV infection.

Authors:  Syria Laperche; Nadine Le Marrec; Annie Girault; Françoise Bouchardeau; Annabelle Servant-Delmas; Michèle Maniez-Montreuil; Pierre Gallian; Thierry Levayer; Pascal Morel; Nicole Simon
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

6.  Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C.

Authors:  A Takaki; M Wiese; G Maertens; E Depla; U Seifert; A Liebetrau; J L Miller; M P Manns; B Rehermann
Journal:  Nat Med       Date:  2000-05       Impact factor: 53.440

7.  Changes in hepatitis C virus (HCV) antibody status in patients with chronic hepatitis C after eradication of HCV infection by interferon therapy.

Authors:  Hidenori Toyoda; Takashi Kumada; Seiki Kiriyama; Yasuhiro Sone; Makoto Tanikawa; Yasuhiro Hisanaga; Teiji Kuzuya; Takashi Honda; Kazuhiko Hayashi; Isao Nakano; Yoshiaki Katano; Hidemi Goto
Journal:  Clin Infect Dis       Date:  2005-02-18       Impact factor: 9.079

8.  Early detection of hepatitis C virus infection by use of a new combined antigen-antibody detection assay: potential use for high-risk individuals.

Authors:  A Schnuriger; S Dominguez; M-A Valantin; R Tubiana; C Duvivier; J Ghosn; A Simon; C Katlama; V Thibault
Journal:  J Clin Microbiol       Date:  2006-04       Impact factor: 5.948

9.  Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort.

Authors:  Jeffrey J Post; Yong Pan; Anthony J Freeman; Charles E Harvey; Peter A White; Patricia Palladinetti; Paul S Haber; George Marinos; Michael H Levy; John M Kaldor; Kate A Dolan; Rosemary A Ffrench; Andrew R Lloyd; William D Rawlinson
Journal:  J Infect Dis       Date:  2004-04-26       Impact factor: 5.226

10.  Occult hepatitis C virus infection in patients in whom the etiology of persistently abnormal results of liver-function tests is unknown.

Authors:  Inmaculada Castillo; Margarita Pardo; Javier Bartolomé; Nuria Ortiz-Movilla; Elena Rodríguez-Iñigo; Susana de Lucas; Clara Salas; Jose A Jiménez-Heffernan; Arturo Pérez-Mota; Javier Graus; Juan Manuel López-Alcorocho; Vicente Carreño
Journal:  J Infect Dis       Date:  2003-12-31       Impact factor: 5.226

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  5 in total

1.  New perspectives in occult hepatitis C virus infection.

Authors:  Vicente Carreño; Javier Bartolomé; Inmaculada Castillo; Juan Antonio Quiroga
Journal:  World J Gastroenterol       Date:  2012-06-21       Impact factor: 5.742

2.  Serum immunoglobulin G antibodies to the GOR autoepitope are present in patients with occult hepatitis C virus (HCV) infection despite lack of HCV-specific antibodies.

Authors:  Juan A Quiroga; Inmaculada Castillo; Javier Bartolomé; Vicente Carreño
Journal:  Clin Vaccine Immunol       Date:  2007-08-15

Review 3.  Occult HCV Infection: The Current State of Knowledge.

Authors:  Mohammad Saeid Rezaee-Zavareh; Reza Hadi; Hamidreza Karimi-Sari; Mohammad Hossein Khosravi; Reza Ajudani; Fardin Dolatimehr; Mahdi Ramezani-Binabaj; Seyyed Mohammad Miri; Seyed Moayed Alavian
Journal:  Iran Red Crescent Med J       Date:  2015-11-29       Impact factor: 0.611

4.  Regulatory polymorphism of CXCL10 rs1439490 in seronegative occult hepatitis C virus infection.

Authors:  Xu Wang; Song Wang; Zhen-Hua Liu; Wen-Qian Qi; Qian Zhang; Yong-Gui Zhang; De-Rong Sun; Yan Xu; Hong-Guang Wang; Zhong-Xie Li; Xian-Ling Cong; Ping Zhao; Chang-Yu Zhou; Jiang-Bin Wang
Journal:  World J Gastroenterol       Date:  2018-05-28       Impact factor: 5.742

Review 5.  A New Twist to a Chronic HCV Infection: Occult Hepatitis C.

Authors:  Bashar M Attar; David Van Thiel
Journal:  Gastroenterol Res Pract       Date:  2015-06-24       Impact factor: 2.260

  5 in total

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