Literature DB >> 17020304

Electrophilic allylations and benzylations of indoles in neutral aqueous or alcoholic solutions.

Martin Westermaier1, Herbert Mayr.   

Abstract

[reaction: see text] Indoles are allylated and benzylated in moderate to quantitative yield when stirred with allyl and benzyl halides in 80% aqueous acetone in the presence of NH(4)HCO(3) at room temperature.

Entities:  

Year:  2006        PMID： 17020304     DOI： 10.1021/ol0618555

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Synthesis of indole analogues of the natural schweinfurthins.

Authors:  John G Kodet; David F Wiemer
Journal:  J Org Chem       Date:  2013-09-05       Impact factor: 4.354

2.  Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase.

Authors:  Qi Qian; Andrew W Schultz; Bradley S Moore; Martin E Tanner
Journal:  Biochemistry       Date:  2012-09-19       Impact factor: 3.162

3.  Friedel-Crafts Alkylation of Indoles with Trichloroacetimidates.

Authors:  Tamie Suzuki; John D Chisholm
Journal:  Tetrahedron Lett       Date:  2019-04-03       Impact factor: 2.415

4.  Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline.

Authors:  Robert J Sharpe; Jeffrey S Johnson
Journal:  J Org Chem       Date:  2015-10-02       Impact factor: 4.354

5.  Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families.

Authors:  Zhanchao Meng; Haixin Yu; Li Li; Wanyin Tao; Hao Chen; Ming Wan; Peng Yang; David J Edmonds; Jin Zhong; Ang Li
Journal:  Nat Commun       Date:  2015-02-04       Impact factor: 14.919
  5 in total

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