| Literature DB >> 17020299 |
Jason Samuel Tan1, Marco A Ciufolini.
Abstract
[reaction: see text] We describe a straightforward synthesis of topopyrones B and D, which are potent and selective inhibitors of topoisomerase I. The chemistry should be suitable for additional structure-activity relationship (SAR) work.Entities:
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Year: 2006 PMID： 17020299 DOI： 10.1021/ol0617291
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005