| Literature DB >> 1701851 |
P Basset1, J P Bellocq, C Wolf, I Stoll, P Hutin, J M Limacher, O L Podhajcer, M P Chenard, M C Rio, P Chambon.
Abstract
A gene has been identified that is expressed specifically in stromal cells surrounding invasive breast carcinomas. On the basis of its sequence, the product of this gene, named stromelysin-3, is a new member of the family of metalloproteinase enzymes which degrade the extracellular matrix. The suggestion is that stromelysin-3 is one of the stroma-derived factors that have long been postulated to play an important part in progression of epithelial malignancies.Entities:
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Year: 1990 PMID： 1701851 DOI： 10.1038/348699a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962