| Literature DB >> 17018273 |
Xi He1.
Abstract
In this issue of Cell, Yang et al. (2006b) show that PDGF, a growth factor that induces the transition of epithelial cells to mesenchymal cells, stimulates the c-Abl kinase-dependent phosphorylation of p68 RNA helicase. Phosphorylated p68 dissociates beta-catenin from the Axin destruction complex, thereby promoting nuclear beta-catenin signaling independent of Wnt activation.Entities:
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Year: 2006 PMID: 17018273 DOI: 10.1016/j.cell.2006.09.016
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582