| Literature DB >> 17017571 |
Abstract
Understanding of the pathophysiology of dystonia derives primarily from studies of focal dystonias. Physiological investigations have revealed a number of abnormalities that may reflect the genetic substrate that predisposes certain individuals to develop dystonia. There is a loss of inhibition in the central nervous system, and a loss of surround inhibition specifically. Plasticity is increased, and there are sensory abnormalities. Which of these disorders is primary is uncertain.Entities:
Mesh：
Year: 2006 PMID： 17017571 DOI： 10.1007/978-3-211-45295-0_72
Source DB: PubMed Journal: J Neural Transm Suppl ISSN： 0303-6995