AIMS: The development of mitral regurgitation (MR) after an acute myocardial infarction (AMI) is a recognized and frequent complication and its negative impact on survival has been observed. However, few data exist regarding MR after non-ST-segment elevation acute coronary syndrome (NSTSEACS). Our aim was to investigate the incidence, clinical predictors, and prognostic implications of MR in the setting of NSTSEACS. METHODS AND RESULTS: We studied 300 consecutive patients (71.7% men, mean age 66.9+/-13 years) admitted to our coronary care unit for an NSTSEACS. Every patient underwent an echocardiographic study during the first week after the index NSTSEACS and was clinically followed up. MR was detected in 42% (126 patients; 88 men, mean age 71.3+/-11 years). Mean follow-up was 425.6+/-194.8 days. Only age and left ventricular (LV) ejection fraction (EF) were found as independent markers of the development of MR; no variable was found as an independent predictor of in-hospital mortality and only MR was found as an independent predictor of long-term outcome. CONCLUSION: MR is frequent after an NSTSEACS. Age and a low LV EF are factors associated to its development. The presence and degree of MR confer a worse long-term prognosis to patients after a first NSTSEACS. Thus, the presence of MR should be specifically assessed in every patient after an NSTSEACS.
AIMS: The development of mitral regurgitation (MR) after an acute myocardial infarction (AMI) is a recognized and frequent complication and its negative impact on survival has been observed. However, few data exist regarding MR after non-ST-segment elevation acute coronary syndrome (NSTSEACS). Our aim was to investigate the incidence, clinical predictors, and prognostic implications of MR in the setting of NSTSEACS. METHODS AND RESULTS: We studied 300 consecutive patients (71.7% men, mean age 66.9+/-13 years) admitted to our coronary care unit for an NSTSEACS. Every patient underwent an echocardiographic study during the first week after the index NSTSEACS and was clinically followed up. MR was detected in 42% (126 patients; 88 men, mean age 71.3+/-11 years). Mean follow-up was 425.6+/-194.8 days. Only age and left ventricular (LV) ejection fraction (EF) were found as independent markers of the development of MR; no variable was found as an independent predictor of in-hospital mortality and only MR was found as an independent predictor of long-term outcome. CONCLUSION: MR is frequent after an NSTSEACS. Age and a low LV EF are factors associated to its development. The presence and degree of MR confer a worse long-term prognosis to patients after a first NSTSEACS. Thus, the presence of MR should be specifically assessed in every patient after an NSTSEACS.
Authors: Xin Zeng; Lin Zou; Robert A Levine; J Luis Guerrero; Mark D Handschumacher; Suzanne M Sullivan; Gavin J C Braithwaite; James R Stone; Jorge Solis; Orhun K Muratoglu; Gus J Vlahakes; Judy Hung Journal: JACC Cardiovasc Interv Date: 2015-01-14 Impact factor: 11.195
Authors: Covadonga Fernández-Golfín; Alberto De Agustin; M Carmen Manzano; Ana Bustos; Tibisay Sánchez; Leopoldo Pérez de Isla; Manuel Fuentes; Carlos Macaya; José Zamorano Journal: Int J Cardiovasc Imaging Date: 2010-09-08 Impact factor: 2.357
Authors: Jung Sun Cho; Ho-Joong Youn; Sung-Ho Her; Maen Won Park; Chan Joon Kim; Gyung-Min Park; Myung Ho Jeong; Jae Yeong Cho; Youngkeun Ahn; Kye Hun Kim; Jong Chun Park; Ki Bae Seung; Myeong Chan Cho; Chong Jin Kim; Young Jo Kim; Kyoo Rok Han; Hyo Soo Kim Journal: J Korean Med Sci Date: 2015-06-10 Impact factor: 2.153
Authors: Martin Andreas; Nicolas Doll; Steve Livesey; Manuel Castella; Alfred Kocher; Filip Casselman; Vladimir Voth; Christina Bannister; Juan F Encalada Palacios; Daniel Pereda; Guenther Laufer; Markus Czesla Journal: Eur J Cardiothorac Surg Date: 2015-02-17 Impact factor: 4.191
Authors: Sadip Pant; Pritam Neupane; Om Biju Pant; Raju Paudel; M P Kavin Kumar; C S Vijayashankar; Rajendra Man Shrestha Journal: Heart Views Date: 2011-07