Literature DB >> 17015305

An ontology of scientific experiments.

Larisa N Soldatova1, Ross D King.   

Abstract

The formal description of experiments for efficient analysis, annotation and sharing of results is a fundamental part of the practice of science. Ontologies are required to achieve this objective. A few subject-specific ontologies of experiments currently exist. However, despite the unity of scientific experimentation, no general ontology of experiments exists. We propose the ontology EXPO to meet this need. EXPO links the SUMO (the Suggested Upper Merged Ontology) with subject-specific ontologies of experiments by formalizing the generic concepts of experimental design, methodology and results representation. EXPO is expressed in the W3C standard ontology language OWL-DL. We demonstrate the utility of EXPO and its ability to describe different experimental domains, by applying it to two experiments: one in high-energy physics and the other in phylogenetics. The use of EXPO made the goals and structure of these experiments more explicit, revealed ambiguities, and highlighted an unexpected similarity. We conclude that, EXPO is of general value in describing experiments and a step towards the formalization of science.

Mesh:

Year:  2006        PMID: 17015305      PMCID: PMC1885356          DOI: 10.1098/rsif.2006.0134

Source DB:  PubMed          Journal:  J R Soc Interface        ISSN: 1742-5662            Impact factor:   4.118


  5 in total

1.  A reference ontology for biomedical informatics: the Foundational Model of Anatomy.

Authors:  Cornelius Rosse; José L V Mejino
Journal:  J Biomed Inform       Date:  2003-12       Impact factor: 6.317

2.  A precision measurement of the mass of the top quark.

Authors:  V M Abazov; B Abbott; A Abdesselam; M Abolins; V Abramov; B S Acharya; D L Adams; M Adams; S N Ahmed; G D Alexeev; A Alton; G A Alves; Y Arnoud; C Avila; V V Babintsev; L Babukhadia; T C Bacon; A Baden; S Baffioni; B Baldin; P W Balm; S Banerjee; E Barberis; P Baringer; J Barreto; J F Bartlett; U Bassler; D Bauer; A Bean; F Beaudette; M Begel; A Belyaev; S B Beri; G Bernardi; I Bertram; A Besson; R Beuselinck; V A Bezzubov; P C Bhat; V Bhatnagar; M Bhattacharjee; G Blazey; F Blekman; S Blessing; A Boehnlein; N I Bojko; T A Bolton; F Borcherding; K Bos; T Bose; A Brandt; G Briskin; R Brock; G Brooijmans; A Bross; D Buchholz; M Buehler; V Buescher; V S Burtovoi; J M Butler; F Canelli; W Carvalho; D Casey; H Castilla-Valdez; D Chakraborty; K M Chan; S V Chekulaev; D K Cho; S Choi; S Chopra; D Claes; A R Clark; B Connolly; W E Cooper; D Coppage; S Crépé-Renaudin; M A C Cummings; D Cutts; H Da Motta; G A Davis; K De; S J De Jong; M Demarteau; R Demina; P Demine; D Denisov; S P Denisov; S Desai; H T Diehl; M Diesburg; S Doulas; L V Dudko; L Duflot; S R Dugad; A Duperrin; A Dyshkant; D Edmunds; J Ellison; J T Eltzroth; V D Elvira; R Engelmann; S Eno; G Eppley; P Ermolov; O V Eroshin; J Estrada; H Evans; V N Evdokimov; T Ferbel; F Filthaut; H E Fisk; M Fortner; H Fox; S Fu; S Fuess; E Gallas; A N Galyaev; M Gao; V Gavrilov; R J Genik; K Genser; C E Gerber; Y Gershtein; G Ginther; B Gómez; P I Goncharov; K Gounder; A Goussiou; P D Grannis; H Greenlee; Z D Greenwood; S Grinstein; L Groer; S Grünendahl; M W Grünewald; S N Gurzhiev; G Gutierrez; P Gutierrez; N J Hadley; H Haggerty; S Hagopian; V Hagopian; R E Hall; C Han; S Hansen; J M Hauptman; C Hebert; D Hedin; J M Heinmiller; A P Heinson; U Heintz; M D Hildreth; R Hirosky; J D Hobbs; B Hoeneisen; J Huang; Y Huang; I Iashvili; R Illingworth; A S Ito; M Jaffré; S Jain; R Jesik; K Johns; M Johnson; A Jonckheere; H Jöstlein; A Juste; W Kahl; S Kahn; E Kajfasz; A M Kalinin; D Karmanov; D Karmgard; R Kehoe; S Kesisoglou; A Khanov; A Kharchilava; B Klima; J M Kohli; A V Kostritskiy; J Kotcher; B Kothari; A V Kozelov; E A Kozlovsky; J Krane; M R Krishnaswamy; P Krivkova; S Krzywdzinski; M Kubantsev; S Kuleshov; Y Kulik; S Kunori; A Kupco; V E Kuznetsov; G Landsberg; W M Lee; A Leflat; F Lehner; C Leonidopoulos; J Li; Q Z Li; J G R Lima; D Lincoln; S L Linn; J Linnemann; R Lipton; A Lucotte; L Lueking; C Lundstedt; C Luo; A K A Maciel; R J Madaras; V L Malyshev; V Manankov; H S Mao; T Marshall; M I Martin; S E K Mattingly; A A Mayorov; R McCarthy; T McMahon; H L Melanson; A Melnitchouk; A Merkin; K W Merritt; C Miao; H Miettinen; D Mihalcea; N Mokhov; N K Mondal; H E Montgomery; R W Moore; Y D Mutaf; E Nagy; M Narain; V S Narasimham; N A Naumann; H A Neal; J P Negret; S Nelson; A Nomerotski; T Nunnemann; D O'Neil; V Oguri; N Oshima; P Padley; K Papageorgiou; N Parashar; R Partridge; N Parua; A Patwa; O Peters; P Pétroff; R Piegaia; B G Pope; H B Prosper; S Protopopescu; M B Przybycien; J Qian; S Rajagopalan; P A Rapidis; N W Reay; S Reucroft; M Ridel; M Rijssenbeek; F Rizatdinova; T Rockwell; C Royon; P Rubinov; R Ruchti; B M Sabirov; G Sajot; A Santoro; L Sawyer; R D Schamberger; H Schellman; A Schwartzman; E Shabalina; R K Shivpuri; D Shpakov; M Shupe; R A Sidwell; V Simak; V Sirotenko; P Slattery; R P Smith; G R Snow; J Snow; S Snyder; J Solomon; Y Song; V Sorín; M Sosebee; N Sotnikova; K Soustruznik; M Souza; N R Stanton; G Steinbrück; D Stoker; V Stolin; A Stone; D A Stoyanova; M A Strang; M Strauss; M Strovink; L Stutte; A Sznajder; M Talby; W Taylor; S Tentindo-Repond; T G Trippe; A S Turcot; P M Tuts; R Van Kooten; V Vaniev; N Varelas; F Villeneuve-Seguier; A A Volkov; A P Vorobiev; H D Wahl; Z-M Wang; J Warchol; G Watts; M Wayne; H Weerts; A White; D Whiteson; D A Wijngaarden; S Willis; S J Wimpenny; J Womersley; D R Wood; Q Xu; R Yamada; T Yasuda; Y A Yatsunenko; K Yip; J Yu; M Zanabria; X Zhang; B Zhou; Z Zhou; M Zielinski; D Zieminska; A Zieminski; V Zutshi; E G Zverev; A Zylberstejn
Journal:  Nature       Date:  2004-06-10       Impact factor: 49.962

Review 3.  Phylogeny and life histories of the 'Insectivora': controversies and consequences.

Authors:  Matthew R E Symonds
Journal:  Biol Rev Camb Philos Soc       Date:  2005-02

4.  Mesozoic origin for West Indian insectivores.

Authors:  Alfred L Roca; Gila Kahila Bar-Gal; Eduardo Eizirik; Kristofer M Helgen; Roberto Maria; Mark S Springer; Stephen J O'Brien; William J Murphy
Journal:  Nature       Date:  2004-06-10       Impact factor: 49.962

5.  Functional genomic hypothesis generation and experimentation by a robot scientist.

Authors:  Ross D King; Kenneth E Whelan; Ffion M Jones; Philip G K Reiser; Christopher H Bryant; Stephen H Muggleton; Douglas B Kell; Stephen G Oliver
Journal:  Nature       Date:  2004-01-15       Impact factor: 49.962

  5 in total
  24 in total

1.  A neuroinformatics of brain modeling and its implementation in the Brain Operation Database BODB.

Authors:  Michael A Arbib; Anon Plangprasopchok; James Bonaiuto; Robert E Schuler
Journal:  Neuroinformatics       Date:  2014-01

2.  Brede tools and federating online neuroinformatics databases.

Authors:  Finn Årup Nielsen
Journal:  Neuroinformatics       Date:  2014-01

3.  Combining ontologies and workflows to design formal protocols for biological laboratories.

Authors:  Alessandro Maccagnan; Mauro Riva; Erika Feltrin; Barbara Simionati; Tullio Vardanega; Giorgio Valle; Nicola Cannata
Journal:  Autom Exp       Date:  2010-04-23

4.  Towards Robot Scientists for autonomous scientific discovery.

Authors:  Andrew Sparkes; Wayne Aubrey; Emma Byrne; Amanda Clare; Muhammed N Khan; Maria Liakata; Magdalena Markham; Jem Rowland; Larisa N Soldatova; Kenneth E Whelan; Michael Young; Ross D King
Journal:  Autom Exp       Date:  2010-01-04

5.  Modeling biomedical experimental processes with OBI.

Authors:  Ryan R Brinkman; Mélanie Courtot; Dirk Derom; Jennifer M Fostel; Yongqun He; Phillip Lord; James Malone; Helen Parkinson; Bjoern Peters; Philippe Rocca-Serra; Alan Ruttenberg; Susanna-Assunta Sansone; Larisa N Soldatova; Christian J Stoeckert; Jessica A Turner; Jie Zheng
Journal:  J Biomed Semantics       Date:  2010-06-22

6.  Structured digital tables on the Semantic Web: toward a structured digital literature.

Authors:  Kei-Hoi Cheung; Matthias Samwald; Raymond K Auerbach; Mark B Gerstein
Journal:  Mol Syst Biol       Date:  2010-08-24       Impact factor: 11.429

7.  Improving the accuracy of therapy descriptions in clinical trials using a bottom-up approach.

Authors:  Maurine Tong; Ricky K Taira
Journal:  AMIA Annu Symp Proc       Date:  2012-11-03

8.  Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case.

Authors:  Thomas A Russ; Cartic Ramakrishnan; Eduard H Hovy; Mihail Bota; Gully A P C Burns
Journal:  BMC Bioinformatics       Date:  2011-08-22       Impact factor: 3.307

9.  The EXACT description of biomedical protocols.

Authors:  Larisa N Soldatova; Wayne Aubrey; Ross D King; Amanda Clare
Journal:  Bioinformatics       Date:  2008-07-01       Impact factor: 6.937

10.  Towards a bioinformatics of patterning: a computational approach to understanding regulative morphogenesis.

Authors:  Daniel Lobo; Taylor J Malone; Michael Levin
Journal:  Biol Open       Date:  2012-11-26       Impact factor: 2.422

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.