Alessandra A Gorgulho1, Antonio A F De Salles. 1. Division of Neurosurgery, David Geffen School of Medicine at UCLA, University of California at Los Angeles (UCLA), Los Angeles, CA 90095, USA. agorgulho@mednet.ucla.edu
Abstract
BACKGROUND: The history of the development of current available techniques to treat TN was reviewed. METHODS: The largest peer-reviewed publications on the surgical treatment of refractory TN were analyzed, considering the pros and cons of each technique. Results of modern peer-reviewed radiosurgery series were presented, taking into consideration the approach of each research article. Radiation doses and targets for radiosurgery were discussed to maximize the understanding of this technique. RESULTS: It is concluded that radiosurgery is the least invasive modality with the fewest side effects, although, to match the results of the competing techniques, a substantial number of patients still need some medication intake. CONCLUSION: Further studies determining the ideal target and radiation dose may bring radiosurgery results to the level of the ones achieved with microvascular decompression, currently considered the gold-standard method.
BACKGROUND: The history of the development of current available techniques to treat TN was reviewed. METHODS: The largest peer-reviewed publications on the surgical treatment of refractory TN were analyzed, considering the pros and cons of each technique. Results of modern peer-reviewed radiosurgery series were presented, taking into consideration the approach of each research article. Radiation doses and targets for radiosurgery were discussed to maximize the understanding of this technique. RESULTS: It is concluded that radiosurgery is the least invasive modality with the fewest side effects, although, to match the results of the competing techniques, a substantial number of patients still need some medication intake. CONCLUSION: Further studies determining the ideal target and radiation dose may bring radiosurgery results to the level of the ones achieved with microvascular decompression, currently considered the gold-standard method.
Authors: Teo Soleymani; David Pieton; Patrick Pezeshkian; Patrick Miller; Alessandra A Gorgulho; Nader Pouratian; Antonio A F De Salles Journal: Surg Neurol Int Date: 2011-10-29
Authors: Karina P Esparza-Moreno; Olivia A García-Garduño; Paola Ballesteros-Zebadúa; José M Lárraga-Gutiérrez; Sergio Moreno-Jiménez; Miguel A Celis-Lopez Journal: J Appl Clin Med Phys Date: 2013-11-04 Impact factor: 2.102
Authors: Emerson Magno de Andrade; André Beer-Furlan; Kleber Paiva Duarte; Erich Talamoni Fonoff; Manoel Jacobsen Teixeira Journal: Surg Neurol Int Date: 2013-11-20