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Literature DB >> 17013971

Total synthesis of tubulysin U and V.

Alexander Dömling¹, Barbara Beck, Uwe Eichelberger, Sukumar Sakamuri, Sanjay Menon, Quin-Zene Chen, Yingchun Lu, Ludger A Wessjohann.

Abstract

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Substances：

Year: 2006 PMID： 17013971 DOI： 10.1002/anie.200601259

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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12 in total

1. Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice.

Authors: William C Floyd; Gopal K Datta; Shinichi Imamura; Heidi M Kieler-Ferguson; Katherine Jerger; Andrew W Patterson; Megan E Fox; Francis C Szoka; Jean M J Fréchet; Jonathan A Ellman
Journal: ChemMedChem Date: 2011-01-03 Impact factor: 3.466

2. Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues.

Authors: Ranganathan Balasubramanian; Bhooma Raghavan; Adrian Begaye; Dan L Sackett; Robert A Fecik
Journal: J Med Chem Date: 2009-01-22 Impact factor: 7.446

3. Coupling Interrupted Fischer and Multicomponent Joullié-Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics.

Authors: Antonella Ilenia Alfano; Elisabetta Buommino; Maria Grazia Ferraro; Carlo Irace; Angela Zampella; Heiko Lange; Margherita Brindisi
Journal: ChemMedChem Date: 2021-10-18 Impact factor: 3.540

9. Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog.

Authors: Gregory K Friestad; Koushik Banerjee; Jean-Charles Marié; Umesh Mali; Lei Yao
Journal: J Antibiot (Tokyo) Date: 2016-02-17 Impact factor: 2.649

Review 10. Applications of ultrasound in total synthesis of bioactive natural products: A promising green tool.

Authors: Sasadhar Majhi
Journal: Ultrason Sonochem Date: 2021-07-18 Impact factor: 7.491

Total synthesis of tubulysin U and V.

1. Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice.

2. Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues.

3. Coupling Interrupted Fischer and Multicomponent Joullié-Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics.

4. Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.

5. Synthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactions.

6. Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles.

7. The multicomponent approach to N-methyl peptides: total synthesis of antibacterial (-)-viridic acid and analogues.

8. Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids.

9. Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog.

Review 10. Applications of ultrasound in total synthesis of bioactive natural products: A promising green tool.